European funds

HORIZON 2020

Welcoming ERA Chair to Centre of excellence in nutrigenomics for optimising health and well-being in the Institute of Animal Reproduction and Food Research, Polish Academy of Sciences

Call No.: WIDESPREAD-06-2020: ERA Chairs

Period: 72 months (10.2020 – 09.2026)

Budget: 2 500 000 EUR,

Coordinator: Prof. Mariusz Piskuła

HORIZON 2020

Towards coordinated microbiom R&I activities in the food system to suport (EU and) international bioeconomy goals (MicrobiomeSupport)

Call No.: H2020 – Sustainable Food Security – Resilient and resource-efficient value chains – H2020-SFS-2018-1

Period: 1.11.2018 – 31.10.2022

Budget of the consortium: € 3 590 466,25

IAR&FR PAS Budget: € 34 000

IAR&FR PAS Coordinator: D.Sc. Wiesław Wiczkowski

https://www.microbiomesupport.eu/

European Institute of Innovation & Technology

EIT Food

Call No.: Food4Future – Sustainable Supply Chain from Resources to Consumers

www.eitfood.eu

Period: 7 years (2017 – 2024)

Budget of the consortium: 4 000 000 EUR

 

HORIZON 2020

granty_fusion2night

Fusion2Night – Follow your scientific passion and join us tonight on Researchers’ Night

www.nocnaukowcow.pan.olsztyn.pl

Project type: Coordination and Support Action (Marie Skłodowska-Curie Actions)

Call No.: H2020-MSCA-NIGHT-2016  GA 722629

Period: 20 months (2016 – 2017)

Budget:  144 700 EUR

Coordinator:  Katarzyna Capłap

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granty_protein2food

Protein2FoodDevelopment of high quality food protein through sustainable production and processing

http://www.protein2food.eu/

Project type: Research and Innovation Action

Call No.: H20202-SFS-2014_2  GA 635727

Period: 60 months (2015 – 2020)

Budget:  8 817 638 EUR

IAR&FR PAS Coordinator: Prof. Ryszard Amarowicz

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granty_Fusion-Night

Fusion Night – Find Your Passion for Science on Researchers’ Night

www.nocnaukowcow.pan.olsztyn.pl

Project type: Coordination and Support Action (Marie Skłodowska-Curie Actions)

Call No.: MSCA-NIGHT-2014  GA 633317

Period: 20 months (2014 – 2015)

Budget: 81 000 EUR

Cooridinator: Katarzyna Capłap

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7th Framework Programme

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TRAFOON – Traditional Food Network to improve the transfer of knowledge for innovation

www.trafoon.eu

Project type: Coordination and Support Action

Call No.: FP7-KBBE-2013-7 GA 613912

Period: 26  months (2013 – 2016)

Budget: 3 999 908 EUR

IAR&FR PAS Coordinator: Prof. Ryszard Amarowicz

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logo_rgb_poziom

REFRESH – Unlocking the potential of the Institute of Animal Reproduction and Food Research for strengthening integration with the European Research Area and regional development

Project type: Coordination and Support Action (REGPOT)

Call No.: FP7-REGPOT-2010-1 GA 264103

Period: 47 months (2010 – 2014)

Budget: 3 150 000 EUR

Coordinator: Prof. Mariusz K. Piskuła

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Structural funds

Concentrated juice from red-flowered apples as an innovative application for products with increased pro-health properties produced under Tymbark brand

Contract number: 00048.DDD.6509.00080.2019.06

Activity: 16 Collaboration Rural Development Program for 2014-2020

Period: 2021-2022

Budget of the consortium: 5 000 000 PLN

IAR&FR PAS budget: 1 025 389 PLN

http://tymbarkepi.pl

Development of innovative fruit and vegetable preserves maintaining the optimal and beneficial composition of health-promoting substances with the use of unique types of carrots and strawberries in order to expand agricultural and processing production

Contract number: 00031.DDD.6509.00050.2019.05

Activity: 16 Collaboration Rural Development Program for 2014-2020

Period: 2021-2022

Budget of the consortium: 4 667 504 PLN

IAR&FR PAS: 1 346 458,35 PLN

http://agrosnovaepi.pl

Center for Environmental Research and Innovative Food Technologies for Quality of Life

Project No.: RPWM.01.01.00-28-0001/20

Activity: RPWM.01.01.00 Modern research infrastructure of public scientific units

Period: 22.06.2020 – 30.09.2023

Budget: 95 403 492, 51 PLN

Center for Environmental Research and Innovative Food Technologies for Quality of Life

Project No.: RPWM.01.01.00-28-0001/17

Activity: RPWM.01.01.00 Modern research infrastructure of public scientific units

Period: 11.08.2016 – 30.05.2022

Budget: 92 898 998.20 PLN

Comprehensive energy modernization of two public buildings of the Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences located in Popielno (district Wierzba)

Project No.: RPWM.04.03.01-28-0015/18

Activity: RPWM.04.03.00 Comprehensive energy modernization of buildings

Period: 09.07.2018 – 30.09.2023

Budget: 1 965 612.37 PLN

Improving the energy efficiency of two public buildings of the Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences located in Popielno and Wejsuny

Project No.: RPWM.04.03.01-28-0016/18

Activity: RPWM.04.03.00 Comprehensive energy modernization of buildings

Period: 05.07.2018 – 30.09.2023

Budget: 959 768.52 PLN

Protection of biodiversity by directing tourist traffic on the Popielno Peninsula in order to protect endangered species and natural habitats – stage I

Project No.: RPWM.05.03.00-28-0002/19

Activity: RPWM. 05.03.00 Protection of biodiversity

Period: 13.11.2018 – 15.12.2020

Budget: 4 650 003.74 PLN

PNEUFISH – pneumatic method of obtaining eggs of fish – the possibility of application and impact on qualitative and quantitative parameters of gametes and welfare of spawners

Project No.: 00002-61724-OR1400001/10

Programme: PO RYBY 2007-2013; Activity 3.5 – Pilot Projects

Period: 2010-2015

Budget: 8 655 812 PLN

Innovative bakery products with health-promoting properties for Warmia and Mazury

Project No.: POKL 08.02.01-28-010/13

Activity: 8.2. Knowledge transfer

Period: 01.08.2013 – 30.06.2015

Budget: 1 673 413 PLN; IAR&FR PAS budget: 681 694 PLN

Sensory analysis as a method of developing and enhancing the products of Warmia and Mazury agri-food industries

Project No.: POKL.08.02.01-28-029/13

Activity: 8.2. Knowledge transfer

Period: 02.12.2013 – 29.06.2015

Budget: 941 894 PLN; IAR&FR PAS budget: 418 975 PLN

Liaison Officer – a network of cooperation and information exchange between science and agri-food industry in the region of Warmia and Mazury

Project No.: POKL.08.02.01-28-038/11

Activity:  8.2 Knowledge transfer

Period: 01.01.2012 – 31.03.2015

Budget: 1 160 984 PLN

Regional centre for research and transfer of knowledge FOOD FOR HEALTH: Investment in research laboratories creating links between cooperative research units and enterprises

Project No.: RPWM.01.01.03-28-003/11 – Stage I; RPWM.01.01.03-28-003/12 – Stage II

Activity: 1.1 Increasing industrial competitiveness

Period: 02.11.2011 – 31.05.2013 – Stage I;   19.01.2012 – 31.12.2013 – Stage II

Budget: 2 650 328 PLN – Stage I; 4 005 771 PLN – Stage II

DR INNO3- Ph.D. Doctorate studies

Project No.: POKL.08.02.01-28-016/12

Activity: 8.2 Knowledge transfer

Period: 01.08.2012 – 31.12.2013

Budget: 2 268 323 PLN

Welcome Project: Nutrition and ambient temperature during early development can reduce susceptibility to obesity

Project No.: WELCOME/2010-4/3

Activity: 1.2 Improved potential of research staff

Period: 2011-2015

Budget: 4 170 741 PLN

www.welcome.pan.olsztyn.pl

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National Centre for Research and Development (NCBR)

MASTITIS

Developement of immunological veterinary medicinal products for the prevention and treatment of dairy cow mastitis, alternative to conventional chemotherapeutic agents and antibiotics

Project type: Smart Growth Operational Programme 2014-2020/ Priority Axis: – IV Increasing the research potential
Consortium: Research and Development Department Of Salmonella Center IMMUNOLAB Ltd., Institute of Animal Reproduction and Food Research PAS
IAR&FR PAS Coordinator: Prof. Dariusz Skarżyński
Agreement No: POIR.04.01.04-00-0030/20-00
Period: 1.10.2020 – 31.12.2023
Total budget:16 105 575 PLN
IAR&FR PAS budget: 5 538 242 PLN

Project co-financed by the European Regional Development Fund

LONGLIFE

Food Fermentations for Purpose: Health Promotion and Biopreservation  

Project type: JPI HDHL Food Processing for Health
Coordinator: Prof. Ryszard Amarowicz
Agreement No: DZP/JPI HDHL FP4H/146/2016
Period: 2016 – 2019
Total budget: 893 376 PLN
NCBR: 893 376 PLN

EXPLORE ME

Exploitation of regenerative potential of mesenchymal stem cells

Project type: STRATEGMED
IAR&FR PAS Coordinator: Prof. Dariusz Skarżyński
Agreement No.: STRATEGMED1/235773/19/NCBR/2016
Period: 2016 – 2018
Total budget: 20 702 704 PLN
IAR&FR PAS budget: 990 000 PLN

FLUVAC

Vaccine against influenza – innovative production of subunit antigens

Project type: Applied Reserach Programme (PBS)
Consortium: The Institute of Biotechnology and Antibiotics,  Institute of Biochemistry and Biophysics PAS, Institute of Animal Reproduction and Food Research PAS,  Gdańsk University
IAR&FR PAS Coordinator: Prof. Hanna Radecka
Agreement No.: PBS2/A7/14/2014
Period: 2014 – 2017
Total budget:  5 731 063 PLN
IAR&FR PAS budget: 468 000 PLN

MOBIT

Development of Personalized Diagnostic of Malignant Tumors based on tumor heterogeneity and integrated genomic, transcriptomic, metabolomic and imaging PET/MRI analysis. Getting Ready for Individualized Therapy

Project type: STRATEGMED
Consortium: Uniwersytet Medyczny w Białymstoku, Uniwersytecki Szpital Kliniczny w Białymstoku, Fundacja Uniwersytetu Medycznego w Białymstoku, Politechnika Białostocka, Institute of Animal Reproduction and Food Research PAS, Wojewódzki Szpital Specjalistyczny w Olsztynie, Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, ideas4biology Sp. z o.o., Instytut Innowacji i Technologii Politechniki Białostockiej Sp. z o.o.
IAR&FR PAS Coordinator: Ph.D., D.Sc. Monika Kaczmarek
Agreement No: STRATEGMED2/266484/2/NCBR/2015
Period: 2015 – 2018
Total budget: 18 905 505 PLN
IAR&FR PAS budget: 2 745 000 PLN

CRYOHATCH

Innovative hatchery – implementation of semen cryopreservation into development of  breeding programs of salmonid fish

Project type: TANGO
Coordinator: Prof. Andrzej Ciereszko
Agreement No: TANGO1/266953/NCBR/2015
Period: 2015 – 2018
Total budget: 1 210 000 PLN

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National Science Centre

The effect of Western diet modified with vegetable oils on the healing process of skin wounds in mice
Call: NCN Opus 25 (reg. no. 2023/49/B/NZ9/01925)
Coordinator: Joanna WIŚNIEWSKA (BUKOWSKA), PhD (IAR&FR PAS) | Marcin TABAKA, PhD (Institute of Physical Chemistry PAS, IPC PAS)
Budget: 3 495 898 PLN (IAR&FR PAS – 2 525 388 PLN | IPC PAS – 970 510 PLN)
Period: 2024-01-04 – 2028-01-03

Investigating the mechanisms of epigenetic memory at the example of the responsiveness of human immune cells to vitamin D
Call: NCN Opus 25 (reg. no. 2023/49/B/NZ9/00402)
Coordinator: Carsten CARLBERG, prof.
Budget: 3 371 280 PLN
Period: 2024-01-09 – 2028-01-08

The effect of macrophages on the miRNA expression profile in equine endometrial fibroblasts
Call: NCN Preludium 22 (reg. no. 2023/49/N/NZ6/01654)
Coordinator: Ewelina ŻEBROWSKA, MSc
Budget: 209 960 PLN
Period: 2024-01-03 – 2027-01-02

Building blocks and energy carriers in the course of mare endometrial fibrosis – identification of metabolic changes and the effect of inflammatory mediators
Call: NCN Preludium 22 (reg. no. 2023/49/N/NZ5/02309)
Coordinator: Anna WÓJTOWICZ, MSc
Budget: 140 000 PLN
Period: 2024-01-03 – 2026-01-02

The Impact of biosequestration on the profile of bioactive compounds and antioxidant activity of extracts from microalgae Chlorella sp.
Call: NCN Miniatura 7 (reg. no. 2023/07/X/NZ9/01688)
Coordinator: Michał JANIAK, PhD
Budget: 49 995 PLN
Period: 2023-11-27 – 2024-11-26

Comparison of the potential of red deer and beef for the formation of bioactive peptides
Call: NCN Miniatura 7 (reg. no. 2023/07/X/NZ9/01550)
Coordinator: Anna KONONIUK, PhD
Budget: 49 999 PLN
Period: 2023-11-27 – 2024-11-26

Antioxidant defense systems of the skin in terms of age and expression of the epidermal transcription factor Foxn1
Call: NCN Miniatura 7 (reg. no. 2023/07/X/NZ4/00537)
Coordinator: Sylwia MACHCIŃSKA-ZIELIŃSKA, PhD
Budget: 49 995 PLN
Period: 2023-09-05 – 2024-09-04

Analysis of the interaction between the transcription factor Foxn1 and selected Wnt pathway elements in mouse skin
Call: NCN Miniatura 7 (reg. no. 2023/07/X/NZ3/00625)
Coordinator: Marta KOPCEWICZ, PhD
Budget: 49 907 PLN
Period: 2023-10-05 – 2024-10-04

Effect of embryonic signals on methylome of the porcine endometrium as a novel mechanism contributing to pregnancy establishment
Call: NCN Opus 24 (reg. no. 2022/47/B/NZ9/02776)
Coordinator: Agnieszka WACŁAWIK, PhD
Budget: 1999 440 PLN
Period: 2023-06-20 – 2027-06-19

Painting or spots? – Unravelling the mechanism of formation and the functional sgnificance of the novel, glioblastoma-specific localization pattern of HCMV (Human Cytomegalovirus) IE1 (immediate early 1) protein
Call: NCN Opus 24 (reg. no. 2022/47/B/NZ6/02446)
Coordinator: Magdalena M. WEIDNER-GLUNDE, PhD
Budget: 4 585 860 PLN
Period: 2023-06-20 – 2027-06-19

EGF, IGF-1 and cumulus cells co-culture system for in vitro maturation of mammalian oocytes as female fertility preservation strategy
Call: NCN Polonez Bis 2 (reg. no. 2022/45/P/NZ3/03982)
Coordinator: Taisiia YURCHUK, PhD
Budget: 1 111 317 PLN
Period: 2023-06-01 – 2025-05-31
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Effect of intestinal microbiota modulation induced by the chicory inulin-type β-fructans on metabolic parameters and biomarkers of the gut-skin axis in chronic skin inflammation
Call: NCN Opus 23 (reg. no. 2022/45/B/NZ9/03004)
Coordinator: Urszula KRUPA-KOZAK, PhD (IAR&FR PAS) | Agnieszka OWCZARCZYK-SACZONEK, prof. (Uniwersity of Warmia and Mazury in Olsztyn, UWM) | Ewa LANGE, PhD (Warsaw University of Life Sciences, SGGW)
Budget: 2 014 890 PLN (IAR&FR PAS – 1 455 460 PLN | UWM – 239 180 PLN | SGGW – 320 250 PLN)
Period: 2023-02-02 – 2027-02-01

Soluble scavenger receptor cysteine-rich domain-containing protein – SSc5D, a new player of innate immunity in turkey (Meleagris gallopavo) semen involved in yellow semen syndrome
Call: NCN Opus 23 (reg. no. 2022/45/B/NZ9/01360)
Coordinator: Mariola SŁOWIŃSKA, PhD
Budget: 2 285 548 PLN
Period: 2023-01-20 – 2027-01-19

The potential of the combined osmoconcentration-lactic fermentation process in shaping the profile of bioactive components of new onion varieties studied in an in-vivo model
Call: NCN Opus 23 (reg. no. 2022/45/B/NZ9/00550)
Coordinator: Katarzyna GRZELAK-BŁASZCZYK, PhD (Lodz University of Technology, PŁ) | Jerzy JUŚKIEWICZ, prof. (IAR&FR PAS)
Budget: 1 111 584 PLN (PŁ – 618 216 PLN | IAR&FR PAS – 493 368 PLN)
Period: 2023-02-15 – 2027-02-14

The effect of age and diet on dWAT lipid metabolism in mouse model
Call: NCN Sonatina 6 (reg. no. 2022/44/C/NZ5/00129)
Coordinator: Katarzyna WALENDZIK, PhD
Budget: 1 394 035 PLN
Period: 2022-10-03 – 2025-10-02

Immunomodulating properties of pre-fermented whey beverage enriched with chokeberry juice and colostru
Call: NCN Preludium Bis 3 (reg. no. 2021/43/O/NZ9/00957)
Coordinator: Barbara WRÓBLEWSKA, prof.
Budget: 688 080 PLN
Period: 2022-10-01 – 2026-09-30

Extracellular Vesicles from Follicular Fluid and sperm capacitation
Call: NCN Preludium Bis 3 (reg. no. 2021/43/O/NZ3/03095)
Coordinator: Aneta ANDRONOWSKA, PhD
Budget: 688 080 PLN
Period: 2022-10-01 – 2026-09-30

Metallopeptides as alternative markers for the construction of electrochemical biosensors
Call: NCN Miniatura 6 (reg. no. 2022/06/X/ST4/01541)
Coordinator: Kamila MALECKA-BATURO, PhD
Budget: 49 500 PLN
Period: 2022-11-23 – 2023-11-22

Characteristics of the 3D in vitro model of the porcine uterine endometrium using scaffolds for long-term cell culture
Call: NCN Miniatura 6 (reg. no. 2022/06/X/NZ9/00705)
Coordinator: Ewelina GORYSZEWSKA-SZCZUREK, PhD
Budget: 49 940 PLN
Period: 2022-10-01 – 2024-07-31

Transcriptomic analysis of muscular layer of the uterus in mares with endometrosis
Call: NCN Miniatura 6 (reg. no. 2022/06/X/NZ5/01258)
Coordinator: Ewa DRZEWIECKA, PhD
Budget: 49 984 PLN
Period: 2022-11-23 – 2023-11-22

National Science Center program for scientists from Ukraine to continue research in Poland
Call: NCN Wsparcie dla Ukrainy (reg. no. 2022/01/3/NZ6/00117)
Coordinator: Taisiia YURCHUK, PhD
Budget: 130 000 PLN
Period: 2022-06-01 – 2023-05-31

Biotope influence on genetic diversity, fitness traits, microbiome and embryonic diapause in the European roe deer
Call: NCN OpusLAP 22 (reg. no. 2021/43/I/NZ9/01077)
Coordinator: Anna KORZEKWA, prof. (IAR&FR PAS) | Elena BUZAN, prof. (University of Primorska, UP)
Budget: IAR&FR PAS – 1 861 012 PLN | UP – 290 156 EURO (Slovenia, ARRS)
Period: 2022-07-27 – 2026-07-26

Exploration of the development, role and functioning of circadian rhythm in early life stages of Perca fluviatilis
Call: NCN Opus 22 (reg. no. 2021/43/B/NZ9/03056)
Coordinator: Katarzyna PALIŃSKA-ŻARSKA, PhD (National Inland Fisheries Research Institute, IRS-PIB) | Daniel ŻARSKI, PhD (IAR&FR PAS)
Budget: 1 563 118 PLN (IRS-PIB – 862 753 PLN | IAR&FR PAS – 700 365 PLN)
Period: 2022-10-03 – 2026-10-02

Towards unraveling the role of carp cold acclimation protein 31 (Cap31) – a new important player in fish antimicrobial defense?
Call: NCN Opus 22 (reg. no. 2021/43/B/NZ9/02869)
Coordinator: Andrzej CIERESZKO, prof.
Budget: 1 802 715 PLN
Period: 2022-06-27 – 2026-06-26

The role of the methylation of the progesterone receptor isoforms A and B promoters in the regulation of bovine corpus luteum function
Call: NCN Opus 22 (reg. no. 2021/43/B/NZ9/02840)
Coordinator: Robert J. RĘKAWIECKI, PhD
Budget: 1 387 384 PLN
Period: 2022-10-03 – 2026-10-02

The role of milk matrix lipids in programming the immunoreactivity of proteins derived from lactic acid bacteria
Call: NCN Sonata 17 (reg. no. 2021/43/D/NZ9/02814)
Coordinator: Anna OGRODOWCZYK, PhD
Budget: 1 799 500 PLN
Period: 2022-07-07 – 2025-07-06

Potential use of peroxiredoxins to improve the quality of cryopreserved bull semen
Call: NCN Sonata 17 (reg. no. 2021/43/D/NZ9/01916)
Coordinator: Agnieszka MOSTEK-MAJEWSKA, PhD
Budget: 1 959 780 PLN
Period: 2022-08-01 – 2025-07-31

Importance of miRNA (miR-21, miR-34a, miR-132 and miR-503) and vimentin in process of progesterone synthesis in granulosa cells of the porcine preovulatory follicle
Call: NCN Preludium 20 (reg. no. 2021/41/N/NZ9/03540)
Coordinator: Paweł LIKSZO, MSc
Budget: 197 640 PLN
Period: 2022-01-17 – 2025-01-16

Establishment of the mechanisms of ovarian tissue activation in pre-pubertal cattle – in vitro and in vivo studies
Call: NCN Opus 21 (reg. no. 2021/41/B/NZ9/03661)
Coordinator: Ilona P. KOWALCZYK-ZIĘBA, PhD
Budget: 1 211 338 PLN
Period: 2022-01-13 – 2025-01-12

KETO-MINOX: The effect of isocaloric, energy-restrictive, KETOgenic diet on Metabolism, Inflammation, Nutrition deficiencies and OXidative stress in women with overweight and obesity
Call: NCN Opus 21 (reg. no. 2021/41/B/NZ9/01278)
Coordinator: Natalia DRABIŃSKA, PhD (IAR&FR PAS) | Jerzy ROMASZKO, PhD (Uniwersity of Warmia and Mazury in Olsztyn, UWM)
Budget: 2 023 584 PLN (IAR&FR PAS – 1 987 584 PLN | UWM – 36 000 PLN)
Period: 2022-01-13 – 2025-01-12

Is metabolic effect of copper nanoparticles reliant on dietary fibre with different physiological function?
Call: NCN Opus 21 (reg. no. 2021/41/B/NZ9/01104)
Coordinator: Jerzy JUŚKIEWICZ, prof. (IAR&FR PAS) | Katarzyna OGNIK, prof. (University of Life Sciences in Lublin, UP-Lublin)
Budget: 1 850 496 PLN (IAR&FR PAS – 1 288 808 PLN | UP-Lublin – 561 688 PLN)
Period: 2022-01-13 – 2026-01-12

The search for the novel mechanisms linking intracellular calcium flux regulation with insulin sensitivity response to regular physical exercise
Call: NCN Opus 21 (reg. no. 2021/41/B/NZ7/03948)
Coordinator: Marek STRĄCZKOWSKI, prof.
Budget: 1 946 500 PLN
Period: 2022-01-11 – 2026-01-10

The secretory function and proliferation activity of endometrium: involvement of phoenixin 14
Call: NCN Preludium Bis 2 (reg. no. 2020/39/O/NZ4/03388)
Coordinator: Magdalena K. KOWALIK, PhD
Budget: 541 600 PLN
Period: 2021-10-01 – 2023-01-04

Development of a platform based on DNA aptamers for simultaneous electrochemical determination of selected Parkinson’s disease biomarkers
Call: NCN Miniatura 5 (reg. no. 2021/05/X/ST4/00336)
Coordinator: Edyta MIKUŁA, PhD
Budget: 49 060 PLN
Period: 2021-10-01 – 2022-09-30

Establisment of novel Expanded Potential Stem Cells (EPSCs) from bovine pre-implantation embryos – in vivo and in vitro characterization studies
Call: NCN OpusLAP 20 (reg. no. 2020/39/I/NZ3/03109)
Coordinator: Izabela WOCŁAWEK-POTOCKA, prof. (IAR&FR PAS) | Monika A. NOWAK-IMIALEK, PhD (Technical University of Munich, TUM)
Budget: IAR&FR PAS – 1 054 720 PLN | TUM – 332 986 EURO (Germany, DFG)
Period: 2021-12-23 – 2024-12-22

Importance of fatty acids and their transporters for placenta development in the pig
Call: NCN Opus 20 (reg. no. 2020/39/B/NZ9/01751)
Coordinator: Agnieszka BLITEK, prof.
Budget: 1 016 800 PLN
Period: 2021-09-30 – 2025-09-29

Alleviation of adverse effects associated with high-fat diet through dietary patterns changes and/or supplementation of various forms of chromium
Call: NCN Opus 20 (reg. no. 2020/39/B/NZ9/00674)
Coordinator: Jerzy JUŚKIEWICZ, prof. (IAR&FR PAS) | Katarzyna OGNIK, prof. (University of Life Sciences in Lublin, UP-Lublin)
Budget: 1 641 686 PLN (IAR&FR PAS – 1 210 728 PLN | UP-Lublin – 431 140 PLN)
Period: 2021-06-24 – 2024-06-23

Do sirtuins regulate epigenetic programming and gene transcription in the endometrium and support conceptus implantation during early pregnancy in pigs?
Call: NCN Sonata 16 (reg. no. 2020/39/D/NZ9/01742)
Coordinator: Magdalena SZYMAŃSKA, PhD
Budget: 1 410 860 PLN
Period: 2021-09-30 – 2024-09-29

Transcriptomic and zootechnical exploration of parental contribution to progeny quality in Eurasian perch, Perca fluviatilis
Call: NCN Sonata Bis 10 (reg. no. 2020/38/E/NZ9/00394)
Coordinator: Daniel ŻARSKI, PhD (IAR&FR PAS) | Katarzyna PALIŃSKA-ŻARSKA, PhD (National Inland Fisheries Research Unstitute, IRS-BIP)
Budget: 2 803 784 PLN (IAR&FR PAS – 2 008 600 PLN | IRS-BIP – 795 184 PLN)
Period: 2021-06-01 – 2026-05-31

Voltage across a hydrogel: A new perspective on cell’s membrane potential and its implications for early embryogenesis
Call: NCN Sonata Bis 10 (reg. no. 2020/38/E/NZ3/00039)
Coordinator: Magdalena KOWACZ, PhD
Budget: 3 368 700 PLN
Period: 2021-07-01 – 2026-06-30

Ultra-sensitive tools for detection of antibiotics as a new strategy to control treatment and withdrawal period after cattle antibiotic therapy
Call: NCN Opus 19 (reg. no. 2020/37/B/NZ9/03423)
Coordinator: Katarzyna KURZĄTKOWSKA-ADASZYŃSKA, PhD
Budget: 1 603 200 PLN
Period: 2021-02-01 – 2025-01-31

The understanding of molecular mechanisms of interactions between macrophages and endometrial fibroblasts in processes related to pathogenesis of endometrosis in mares
Call: NCN Opus 19 (reg. no. 2020/37/B/NZ9/03355)
Coordinator: Anna Z. SZÓSTEK-MIODUCHOWSKA, PhD
Budget: 2 021 640 PLN
Period: 2021-09-01 – 2025-08-31

The role of embryonic signal in epigenetic regulation of genes involved in corpus luteum function during early pregnancy in the pig
Call: NCN Opus 19 (reg. no. 2020/37/B/NZ9/03205)
Coordinator: Piotr KACZYŃSKI, PhD
Budget: 1 167 000 PLN
Period: 2021-03-01 – 2025-02-28

Immune mechanisms facilitating placentation in mares
Call: NCN Sonatina 4 (reg. no. 2020/36/C/NZ9/00192)
Coordinator: Joanna JAWORSKA, PhD
Budget: 1 251 307 PLN
Period: 2020-11-02 – 2024-11-01

Proteomic insights into the mechanism of the acrosome reaction in sturgeon (Acipenser baerii) spermatozoa
Call: NCN Opus 18 (reg. no. 2019/35/B/NZ9/03501)
Coordinator: Mariola A. DIETRICH, PhD
Budget: 1 165 008 PLN
Period: 2020-09-30 – 2025-09-29

The interaction of T helper cells subsets with endometrial fibroblasts in processes associated to development of mare endometrosis
Call: NCN Sonata 15 (reg. no. 2019/35/D/NZ9/02989)
Coordinator: Anna Z. SZÓSTEK-MIODUCHOWSKA, PhD
Budget: 1 503 600 PLN
Period: 2020-09-01 – 2024-08-31

Role of prokineticin 1 in processes related with function of porcine corpus luteum during early pregnancy and the estrous cycle
Call: NCN Preludium 18 (reg. no. 2019/35/N/NZ9/03986)
Coordinator: Monika BARYŁA, MSc
Budget: 210 000 PLN
Period: 2020-11-03 – 2023-11-02

Characterisation of leptin signalling in the obese uteri: putative link to transcriptional regulation during pre-decidualisation
Call: NCN Preludium 18 (reg. no. 2019/35/N/NZ4/03496)
Coordinator: Edyta WALEWSKA, MSc
Budget: 140 000 PLN
Period: 2020-06-25 – 2023-06-24

Evaluation of reproductive hormones and ovarian structure profiles during different reproductive status in wild female Eurasian beaver
Call: NCN Miniatura 4 (reg. no. 2020/04/X/NZ9/01711)
Coordinator: Jumpei TOMIYASU, PhD
Budget: 49 997 PLN
Period: 2020-12-12 – 2022-03-11

Maternal obesity and epigenetic and metabolic regulations during gametogenesis and early embryo development in mice: the specific role of leptin signalling
Call: NCN Sonata Bis 9 (reg. no. 2019/34/E/NZ4/00349)
Coordinator: António M. GALVÃO, PhD
Budget: 3 879 750 PLN
Period: 2020-12-01 – 2024-11-30

Role of epidermally expressed transcription factor Foxn1 in regulation and modulation of dermal white adipose tissue (dWAT)
Call: NCN Preludium 16 (reg. no. 2018/31/N/NZ5/00400)
Coordinator: Katarzyna WALENDZIK, MSc
Budget: 139 993 PLN
Period: 2019-07-09 – 2022-07-08

Mitochondrial and metablolic adjustments during bovine in vitro embryo development – examination of the molecular quality markers of the bovine oocytes
Call: NCN Opus 16 (reg. no. 2018/31/B/NZ9/03412)
Coordinator: Izabela WOCŁAWEK-POTOCKA, prof.
Budget: 1 142 536 PLN
Period: 2019-07-05 – 2023-10-04

Milky Way to reproductive success: role of leptin in the programming of reproductive functions over generations
Call: NCN Opus 16 (reg. no. 2018/31/B/NZ4/03527)
Coordinator: Monika M. KACZMAREK, prof.
Budget: 2 195 550 PLN
Period: 2019-09-03 – 2024-09-02

Polyphenols from raspberries and their metabolites as factors regulating mechanisms of nonalcoholic fatty liver disease
Call: NCN Sonata 14 (reg. no. 2018/31/D/NZ9/02196)
Coordinator: Bartosz FOTSCHKI, PhD
Budget: 1 295 260 PLN
Period: 2019-06-18 – 2023-06-17

Regulation of bull sperm capacitation by redox modifications of proteins
Call: NCN Opus 15 (reg. no. 2018/29/B/NZ9/00486)
Coordinator: Andrzej CIERESZKO, prof.
Budget: 1 706 700 PLN
Period: 2019-01-09 – 2022-07-08

Biological study and mathematical modeling to describe and predict new processes controlling the development, function and atresia of ovarian follicles in cows
Call: NCN Opus 15 (reg. no. 2018/29/B/NZ9/00391)
Coordinator: Dariusz J. SKARŻYŃSKI, prof.
Budget: 1 966 000 PLN
Period: 2019-01-24 – 2024-12-23

Role of microRNAs and prostaglandis in reglation of extracellular vesicles biogenesis in porcine trophoblast cells: in vitro studies
Call: NCN Preludium 15 (reg. no. 2018/29/N/NZ9/02331)
Coordinator: Maria GUZEWSKA, MSc
Budget: 139 993 PLN
Period: 2019-03-15 – 2022-03-14

The mechanisms regulating sperm maturation and formation of cryoinjuries to cryopreserved semen of sex-reversed females rainbow trout
Call: NCN Preludium 15 (reg. no. 2018/29/N/NZ9/00761)
Coordinator: Sylwia JUDYCKA, MSc
Budget: 209 998 PLN
Period: 2019-01-31 – 2022-01-30

Methods of mitochondrial calcium uniporter protein deposition on the gold electrodes surface
Call: NCN Miniatura 2 (reg. no. 2018/02/X/ST4/02565)
Coordinator: Katarzyna KURZĄTKOWSKA, PhD
Budget: 44 550 PLN
Period: 2019-03-15 – 2020-03-14

Effects of embrionic signal on the conceptus and on global gene expression and DNA methylation in the endometrium in pigs in vivo
Call: NCN Opus 14 (reg. no. 2017/27/B/NZ9/03014)
Coordinator: Agnieszka WACŁAWIK, PhD
Budget: 999 628 PLN
Period: 2018-08-31 – 2022-08-30

Effect of sexual maturity and hormonal stimulation on ovarian follicles function in gilts
Call: NCN Opus 14 (reg. no. 2017/27/B/NZ9/02289)
Coordinator: Adam J. ZIĘCIK, prof.
Budget: 1 099 930 PLN
Period: 2018-07-24 – 2022-03-23

Hypoxia inducible factor (Hif-1α) and transcription factor Foxn1 guide regenerative vs reparative skin wound healing processes
Call: NCN Opus 14 (reg. no. 2017/27/B/NZ5/02610)
Coordinator: Barbara GAWROŃSKA-KOZAK, PhD
Budget: 1 994 940 PLN
Period: 2018-08-10 – 2023-02-09

Role of membrane progesterone recptors in the regulation of endometrium activity
Call: NCN Opus 14 (reg. no. 2017/27/B/NZ4/02973)
Coordinator: Magdalena K. KOWALIK, PhD
Budget: 896 360 PLN
Period: 2018-08-03 – 2024-02-02

Exploring mechanisms of congenital HCMV infection: replication, spread and latency establishment
Call: NCN Sonata Bis 7 (reg. no. 2017/26/E/NZ6/01124)
Coordinator: Magdalena M. WEIDNER-GLUNDE, PhD
Budget: 3 179 500 PLN
Period: 2018-05-10 – 2025-05-09

The role of hypoxia-stimulated adipose-derived stromal/stem cells (ASCs) in activation of regenerative (scarless) wound healing pathways in skin
Call: NCN Sonata 13 (reg. no. 2017/26/D/NZ5/00556)
Coordinator: Joanna BUKOWSKA, PhD
Budget: 1 224 304 PLN
Period: 2018-04-27 – 2022-10-26

Antibody-redox active molecule conjugates as platform for simultaneous electrochemical determination of low density lipoprotein (LDL) and oxidized low density lipoprotein (oxLDL)
Call: NCN Opus 13 (reg. no. 2017/25/B/ST4/00139)
Coordinator: Iwona GRABOWSKA, PhD
Budget: 577 580 PLN
Period: 2018-04-30 – 2023-04-29

Production of selected hormones in the reproductive tract of nonpragnant and pregnant females and characteristic of oocytes and biological parameters of semen (Cervus elaphus L.)
Call: NCN Opus 13 (reg. no. 2017/25/B/NZ9/02544)
Coordinator: Anna J. KORZEKWA, PhD
Budget: 1 142 600 PLN
Period: 2018-02-26 – 2022-10-25

The mechanism of pesticides action on activity of bovine cervix and the estimation of their potential adverse effect on reproductive success
Call: NCN Opus 13 (reg. no. 2017/25/B/NZ9/01620)
Coordinator: Michał H. WRÓBEL, PhD
Budget: 406 980 PLN
Period: 2018-01-19 – 2021-01-18

Analysis of miRNA expression profile in the course of mare endometrial fibrosis (endometrosis)
Call: NCN Miniatura 1 (reg. no. 2017/01/Z/NZ5/01528)
Coordinator: Anna Z. SZÓSTEK-MIODUCHOWSKA, PhD
Budget: 49 500 PLN
Period: 2017-12-22 – 2018-12-21

Are there differences in molecular mechanisms and signaling pathways of PGF2A-induced bovine luteal cell death depending upon its peripheral or local administration: comparison between endocrine and paracrine effects
Call: NCN Miniatura 1 (reg. no. 2017/01/X/NZ9/00363)
Coordinator: Katarzyna PIOTROWSKA-TOMALA, PhD
Budget: 44 550 PLN
Period: 2017-09-20 – 2018-09-19

Nutritional and health promoting properties of diets supplemented with seeds or oils from seeds of some plants
Call: NCN Opus 12 (reg. no. 2016/23/B/NZ9/01012)
Coordinator: Adam JURGOŃSKI, PhD
Budget: 522 548 PLN
Period: 2017-08-25 – 2021-02-24

Maternal obesity and epigenetic programming: from gametogenesis to early embryo development
Call: NCN Opus 12 (reg. no. 2016/23/B/NZ4/03737)
Coordinator: António M. GALVÃO, PhD
Budget: 795 756 PLN
Period: 2017-08-24 – 2021-08-23

The analysis of physial and chemical properties of powders obtained from the juices and pomace of selected fruits using different drying methods and determination of their influence on the chosen indicators of the immune system in in vivo model studies
Call: NCN Sonata 12 (reg. no. 2016/23/D/NZ9/02671)
Coordinator: Anna MICHALSKA, PhD
Budget: 479 160 PLN
Period: 2017-10-16 – 2022-04-15

Prostacyclin (PGI2) signaling in in vitro produced bovine embryos derived from oocytes collected in vivo by ovum pick up (oPU) method from prepubertal and pubertal heifers, and cows
Call: NCN Preludium 12 (reg. no. 2016/23/N/NZ9/01554)
Coordinator: Arkadiusz NOWICKI, MSc
Budget: 149 784 PLN
Period: 2017-07-11 – 2022-01-10

Integrated analysis of transcriptome and proteome as a tool for assessment of quality and ageing process in eggs of pikeperch
Call: NCN Harmonia 8 (reg. no. 2016/22/M/NZ9/00590)
Coordinator: Daniel ŻARSKI, PhD (Uniwersity of Warmia and Mazury in Olsztyn, UWM) | Andrzej CIERESZKO, prof. (IAR&FR PAS)
Budget: 1 101 685 PLN (UWM – 698 685 PLN | IAR&FR PAS – 403 000 PLN)
Period: 2017-06-01 – 2021-12-31

Redox active monolayers for exploring of anion recognitions precesses in aqueous phase
Call: NCN Opus 11 (reg. no. 2016/21/B/ST4/03834)
Coordinator: Jerzy J. RADECKI, prof.
Budget: 522 600 PLN
Period: 2017-02-23 – 2020-02-22

Dynamic changes of carp seminal proteins and their modifications upon sperm maturation, hormonal stimulation and storage of semen
Call: NCN Opus 11 (reg. no. 2016/21/B/NZ9/03620)
Coordinator: Mariola A. DIETRICH, PhD
Budget: 587 714 PLN
Period: 2017-02-27 – 2021-02-26

Role of STAT signaling in porcine endometrial remodeling and embryo attachment
Call: NCN Opus 11 (reg. no. 2016/21/B/NZ9/03616)
Coordinator: Beenu MOZA JALALI, PhD
Budget: 659 850 PLN
Period: 2017-02-24 – 2021-10-23

Characterization and biological role of cysteine rich secretory protein (CRISP) in the male reproductive system of turkey (Meleagris gallopavo)
Call: NCN Opus 11 (reg. no. 2016/21/B/NZ9/03583)
Coordinator: Mariola SŁOWIŃSKA, PhD
Budget: 711 346 PLN
Period: 2017-02-26 – 2021-08-25

Extracellular vesicles as an element of maternal-embryo communication during early pregnancy in pig- impact of carried miRNA on recipient cells
Call: NCN Preludium 11 (reg. no. 2016/21/N/NZ9/03443)
Coordinator: Joanna NAJMUŁA, MSc
Budget: 149 976 PLN
Period: 2017-01-24 – 2020-07-23

Influence of supplementation of gluten-free diet with the mixture of short and long chain inulin-type fructans on the profile of volatile organic compounds in urine of coeliac disease children
Call: NCN Preludium 11 (reg. no. 2016/21/N/NZ9/01510)
Coordinator: Natalia DRABIŃSKA, MSc
Budget: 94 200 PLN
Period: 2017-01-18 – 2019-01-17

Studies of the permeation of anthocyanins and their metabolites through the brain barriers in the context of the preventive strategies of neurodegenerative diseases
Call: NCN Opus 9 (reg. no. 2015/17/B/NZ9/01733)
Coordinator: Wiesław WICZKOWSKI, PhD
Budget: 699 900 PLN
Period: 2016-02-15 – 2020-02-14

Ścieżka sygnałowa prostanoidów podczas rozwoju in vitro zarodków bydlęcych
Call: NCN Opus 9 (reg. no. 2015/17/B/NZ9/01688)
Coordinator: Izabela WOCŁAWEK-POTOCKA, PhD
Budget: 941 820 PLN
Period: 2016-02-22 – 2020-02-21

Prostanoid signaling during in vitro development of the bovine embryos
Call: NCN Opus 9 (reg. no. 2015/17/B/NZ9/01623)
Coordinator: Magdalena SURMA, PhD (University of Agriculture in Krakow, UR-Kraków) | Wiesław WICZKOWSKI, PhD (IAR&FR PAS)
Budget: 521 440 PLN (UR-Kraków – 331 480 PLN | IAR&FR PAS – 189 960 PLN)
Period: 2016-04-19 – 2019-10-18

Proteomic characteristic of rainbow trout sperm maturation, motility activation and triploidization
Call: NCN Opus 9 (reg. no. 2015/17/B/NZ9/01542)
Coordinator: Joanna J. NYNCA, PhD
Budget: 604 628 PLN
Period: 2016-03-03 – 2021-09-02

Impact of high hydrostatic pressure on the profile of bioactive compounds, antioxidant activity, enzyme and microbial stability of pulp obtained from selected varieties of tomato
Call: NCN Opus 9 (reg. no. 2015/17/B/NZ9/01532)
Coordinator: Wioletta BŁASZCZAK, PhD
Budget: 526 090 PLN
Period: 2016-05-13 – 2019-05-12

Coactivators and corepressors of progesterone receptors as a regulators of progesterone influence on the tissues in the repdoductive track in cow
Call: NCN Opus 9 (reg. no. 2015/17/B/NZ4/02440)
Coordinator: Robert J. RĘKAWIECKI, PhD
Budget: 445 000 PLN
Period: 2016-02-08 – 2020-12-07

The effect of Lactobacillus strains and transglutaminase on immunoreactivity of beta-lactoglobulin and α-casein in mare’s milk
Call: NCN Preludium 9 (reg. no. 2015/17/N/NZ9/03666)
Coordinator: Joanna FOTSCHKI, MSc
Budget: 99 960 PLN
Period: 2016-01-19 – 2019-07-18

Determination of absorption possibility of beetroot betalains from the stomach in in vivo model
Call: NCN Preludium 9 (reg. no. 2015/17/N/NZ9/01141)
Coordinator: Tomasz SAWICKI, MSc
Budget: 99 720 PLN
Period: 2016-01-19 – 2018-01-18

Autocrine, juxtacrine and paracrine actions of miRNAs in early stages of pregnancy in pigs
Call: NCN Opus 8 (reg. no. 2014/15/B/NZ9/04932)
Coordinator: Monika M. KACZMAREK, PhD
Budget: 826 800 PLN
Period: 2015-07-17 – 2019-03-16

Metabolomic and antioxidative profiles of fermented buckwheat flours and phytochemicals bioaccessibility in a model of water buckwheat biscuits in the context of pro-healthy properties
Call: NCN Opus 8 (reg. no. 2014/15/B/NZ9/04461)
Coordinator: Henryk ZIELIŃSKI, prof.
Budget: 681 590 PLN
Period: 2015-07-21 – 2019-07-20

Effect of experimentally – induced inflammatory process of uterus on its innervation and role of neurotransmitters in the pathologically – changed organ function in pig
Call: NCN Opus 8 (reg. no. 2014/15/B/NZ5/03572)
Coordinator: Barbara JANA, prof.
Budget: 783 000 PLN
Period: 2015-07-15 – 2018-07-14

Role of leptin in the pathogenesis of ovarian dysfunction during obesity progression
Call: NCN Sonata 8 (reg. no. 2014/15/D/NZ4/01152)
Coordinator: António M. GALVÃO, PhD
Budget: 683 099 PLN
Period: 2015-07-15 – 2019-04-14

PPAR: PPARalpha, PPARbeta/delta, PPARgamma expression profile in the bovine corpus luteum during estrous cycle and under the influence of PGF2alpha
Call: NCN Preludium 8 (reg. no. 2014/15/N/NZ9/02428)
Coordinator: Barbara M. SOCHA, MSc
Budget: 150 000 PLN
Period: 2015-07-21 – 2019-03-20

In vivo studies on health-promoting properties of raspberry pomace with the disparate content and origin of bioactive compounds
Call: NCN Preludium 8 (reg. no. 2014/15/N/NZ9/02425)
Coordinator: Bartosz FOTSCHKI, MSc
Budget: 150 000 PLN
Period: 2015-07-20 – 2018-07-19

The role of vascular endothelial growth factor in bovine uterus during adenomyosis
Call: NCN Preludium 8 (reg. no. 2014/15/N/NZ9/02414)
Coordinator: Martyna ŁUPICKA, MSc
Budget: 150 000 PLN
Period: 2015-07-21 – 2018-07-20

Does prostaglandin E2 (PGE2) synthesis and PGE2 receptors expression in the in vitro cultured bovine embryos reflect the quality of oocytes
Call: NCN Preludium 7 (reg. no. 2014/13/N/NZ9/03924)
Coordinator: Dorota BORUSZEWSKA, PhD
Budget: 150 000 PLN
Period: 2015-02-06 – 2018-08-05

The involvement of hypoxia and subunit alpha of hypoxia inducible factor (HIF-1alpha) in regression of corpus luteum in the pig
Call: NCN Preludium 7 (reg. no. 2014/13/N/NZ9/01062)
Coordinator: Emilia PRZYGRODZKA, MSc
Budget: 100 000 PLN
Period: 2015-03-02 – 2017-03-01

The role of prostacyclin and its receptors in luteal and endothelial cells of the porcine corpus luteum
Call: NCN Preludium 7 (reg. no. 2014/13/N/NZ9/00711)
Coordinator: Magdalena SZYMAŃSKA, MSc
Budget: 149 500 PLN
Period: 2015-02-27 – 2018-02-26

The role of lysophosphatidic (LPA) and sphingosine-1-phosphate (S1P) and their receptors in human endometrial stromal cells proliferation, migration and decidualization
Call: NCN Preludium 7 (reg. no. 2014/13/N/NZ4/04408)
Coordinator: Maria SZTACHELSKA, MSc
Budget: 149 500 PLN
Period: 2015-02-12 – 2018-08-11

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Ministry of Science and Higher Education

National Leading Science Centre (KNOW)

Title: Scientific Consortium „Healthy Animal – Safe food”
IAR&FR PAS Coordinator: Prof. Dariusz Skarżyński
Decision No.: 05-1/KNOW2/2015
Period: 2015-2019
Total budget: 41 476 000 PLN
IAR&FR PAS budget: 8 295 200 PLN

Iuventus Plus

Title: The role of myofibroblasts in chronic degenerative endometritis in the mare
Coordinator: Ph.D. Anna Szóstek
Agreement No.: 0463/IPI/2015/73
Period: 2015-03-16 / 2017-03-15
Total Budget: 200 000 PLN

Title: The impact of the of transforming growth factor ß superfamily on the function of corpus luteum in mare
Coordinator: DVM, Ph.D., D.Sc. Antonio Galvao
Agreement No.: 0113/IPI/2015/73
Period: 2015-03-25 / 2017-03-24
Total Budget: 180 000 PLN

Diamentowy Grant

Title: Embryonic/endometrial exosomes as a new component of embryo-maternal interaction in the pig
Coordinator: Joanna Najmuła
Agreement No.: 0041/DIA/2014/43
Period: 2014-09-15 / 2016-09-14
Total Budget: 170 555 PLN

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Methods and analysis

  • examination of the level of phytochemicals metabolites in biological fluids and tissues of organisms;
  • analysis of metabolic biomarkers upon plant food intake;
  • bioavailability study of food compounds and determination of pharmacokinetic parameters;
  • analysis of plant metabolome;
  • qualitative and quantitative analysis of phytocompounds.

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Equipment

  1. micro-UHPLC gradient system with autosampler (LC200, Eksigent) coupled with TripleTOF 5600+ mass spectrometer (AB SCIEX, USA);
  2. micro-UHPLC gradient system with autosampler (LC200, Eksigent) coupled with QTRAP 5500 mass spectrometer (AB SCIEX, USA);
  3. HPLC gradient system with autosampler (LC-20) coupled with SPD-M20A DAD detector (Shimadzu, Japan);
  4. HPLC gradient system with autosampler (LC-10, Shimadzu, Japan) coupled with DAD detector (SPD-M10AVP, Shimadzu, Japan) and mass spectrometer (LCMS- QP8000α, Shimadzu, Japan);
  5. HPLC gradient system with autosampler (LC-10, Shimadzu, Japan) coupled with UV-Vis detector (SPD-10A, Shimadzu, Japan) and fluorescence detector (RF-10AXL, Shimadzu, Japan);
  6. HPLC gradient system with autosampler (LPG-3400M, WPS-3000TSL, Dionex, USA) coupled with multi-channel electrochemical detector (5600A, ESA, USA) and fluorescence detector (FLD-3400RS, Dionex, USA);
  7. HPLC isocratic system (LC-10, Shimadzu, Japan) coupled with two electrochemical detectors (ICA-3000, TOA, Japan and ED40, Dionex, USA);
  8. gas chromatograph (7890A, Agilent, USA) with MS and FID detectors;
  9. software for pharmacokinetic calculation Biokinetica.

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Methods and analysis

  1. Immunoenzymatic (ELISA) and immunoizotopic (RIA) determination of hormone concentrations:
    • protein hormones (LH, PRL) and receptors LH/hCG with iodine (J-125)-labelled preparation,
    • iodination of protein hormones (LH, PRL) and cytokine (IL-1β, IL-6, TNF-α),
    • steroid hormones (P4, A4, T, E1, E2, cortisol),
    • prostaglandins (PGE2, PGF2α) and metabolite of PGF2α – PGFM,
    • Oxytocin and endothelins using preoxidase (HRP)- or biotin conjugated hormones
  2. Analysis of critical parameters and blood gasometry:

    Analysis of gasometry and oxymetry parameters as well as electrolytes, with application of analyser of critical parameters, RAPIDpoint 405 (SIEMENS):

    • gasometry : pH, pCO2, pO2,
    • electrolytes : NA+, K+, Ca++, Cl-,
    • glucose, HCT,
    • oxymetry: sO2, FO2Hb, FCOHb, FHHb, FMetHb, THb,

    together with a number of counted derivative parameters and many parameters of derivatives.

  3. Morphometric blood analysis:

    • Double-track measurement of leucocytes in two independent channels
    • Basic and expanded morphologic analysis of cattle, sheep, horse, cat, dog, rabbit, guinea pig, rat and mouse blood, using of hematologic analyzer ADVIA 2120i (SIEMENS).

    Desired volume of blood sample foranalysis is 157 µl.

  4. Immunochemical-chemiluminescense blood analysis with application of immunochemical analyzer IMMULITE®1000 (SIEMENS):

    • Analysis of adrenal/ pituitary, sex hormone concentrations (e.g. P4, T, E2, cortisol),
    • Analysis of thyroid physiology,
    • Analysis of concentrations of growth factors,
    • Analysis of inflammatory factors (IL-1β, TNF-α, IL-10, LBP),
    • Analysis of allergy, anaemia and diabetes factors,
    • Analysis of cardiologic, infectious disease, cancer factors,
    • Drug concentrations

    Analyses may be conducted with the following material: sera, plasma and culture media.

  5. Analysis of specific immunoglobulins E using ImmunoCAP 100 apparatus:

    • Phadiatop test for differentiation of atopic and non-atopic diseases,
    • Total IgE,
    • Total IgE (low level) – for small children,
    • Specific IgE – over 500 allergies and 70 mixes,
    • Eosynophilic protein ECP – monitoring of asthma treatment,
    • tryptase – monitoring of anaphylaxis,
    • gliadins IgA and IgG – child food intolerance,
    • specific IgA reference to milk proteins,
    • specific IgG and IgG4,
    • anti-thyroid antibodies: anti-TPO, anti-TG,
    • above 22 parameters within autoimmunological diseases in IgG, IgA classes.

    Material required for analysis: 40 µl of patient serum.

  6. Qualitative and quantitative in vitro determination of human IgG and IgE with the use of Euroimmun equipment:

    • Immunoblott to determine specific allergenic IgE antibodies in human sera,
    • The panels concerning mix of 20 allergens in one strip (pollen, pollen-pediatric, food, atopic), two for insect venoms and „pediatric profile” concerning 27 the most popular allergens i.a.: white and yolk of egg, milk proteins, wheat flour, rice, soy, fruits and vegetables within food allergens, and grass and tree pollens, Dermatophagoides allergens, and animals epidermis within pollen allergens.

    Material required for analysis: 100 µl of patient sera.

  7. Detection of functional proteins (cytokines, effector proteins, receptors, cell surface markers or antibodies) released by single cells with the use of ELISpot (Enzyme-Linked ImmunoSpot Assay).

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COST

COST Action CA21139 – 3Rs concepts to improve the quality of biomedical science (IMPROVE).

COST Action CA21149 – Reducing acrylamide exposure of consumers by a cereals supply-chain approach targeting asparagine (ACRYRED).

COST Action CA20128 – Promoting Innovation of ferMENTed fOods.

COST Action ​CA18113 – Understanding and exploiting the impacts of low pH on micro-organisms.

Completed Actions

COST Action CA16119 CellFit – In vitro 3-D total cell guidance and fitness.

COST Action FA1402 ImpARAS – Improving Allergy Risk Assessment Strategy for new food proteins.

COST Action FA1403 POSITIVe – Interindividual variation in response to consumption of plant food bioactives and determinants involved.

COST Action FA 1205 AQUAGAMETE – Assessing and improving the quality of aquatic animal gametes to enhance aquatic resources – The need to harmonize and standardize evolving methodologies, and improve transfer from academia to industry.

COST Action FA1201 EPICONCEPT – Epigenetics and Periconception Environment.

COST Action FA1005 INFOGESTImproving health properties of food by sharing our knowledge on the digestive process

COST Action FA0702 GEMINI – Maternal Interaction With Gametes and Embryo.

COST Action FA0801 LarvaNet – Critical success factors for fish larval production in European Aquaculture: a multidisciplinary network.

COST 926 – Impact of new technologies on the health benefits and safety of bioactive plant compounds.

COST 927 – Thermally processed foods: possible health implications.

COST Action 958 – Viticulture: biotic and abiotic stress – grapevine defence mechanism and grape development.

COST Action D31 – Novel and specific anion receptors for use in sensor technology.

COST FA802 – Feed for health.

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Equipment

  1. Work station designated to immunoenzymatic analysis of hormone concentration (ELISA) consists of:
    • ELISA microplate reader (KHB)
    • Spectrophotometer working with cuvetes and microplates (Multiscan Spectrum, Thermo Scientific)
    • Automatic well washer
    • Microplate incubator (Heraeus)
  2. Work station designated to immunoisotopic analysis of hormone concentration (RIA) consists of:
    • Beta radiation counter
    • Gamma radiation counter
    • Radiochemical hood
    • Beckman centrifuge
    • Hamilton microlab
    • Laboratorial scales
    • Deep-freezer (-85°C)
  3. Chemiluminescent  analyser IMMULITE® 1000:
    • enables analysis of over 90 tests
    • enables simultaneous analysis of 5 different parameters in one sample
    • automatic dilutions for selected tests
    • efficiency 129 tests per hour
    • enables conduction of analysis in the standard and “Turbo” mode
  4. ImmunoCAP 100:
    • fully automatic providing automatic sampling, and printing results obtained
    • the max capacity of the carousel is 48 wells
    • the max time required for conduction of the analysis is 2.4 hours
    • automatic sample dilution
    • simultaneous conduction of several analysis within one sample of the blood serum
  5. EuroimmunQuantitative in vitro tests designated to determine human IgG antibodies against selected antigens (autoimmunological and infectious diseases) as well as specific IgE directed to allergens. The set consists of test stripes with pure allergens along with set of reagents. Data analysis is conducted with EURLineScan programme.
  6. ELISpot (Enzyme-Linked ImmunoSpot Assay)
    • EliScan – scan to read the spots
    • Eli Analyse – software for computer analysis enables automatic background correction, algorithms of contaminant determination, calculation of spot size, intensity, shape and color, Dual-Color analysis, statistical evaluation of replicates, analysis of microplates series.

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