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Publications

Institute of Animal Reproduction and Food Research of PAS > Regenerative Biology Team > Publications

2023

  1. Machcinska-Zielinska, Sylwia; Gawronska-Kozak, Barbara. Epidermal factor Foxn1 as a regulator of skin’s antioxidant defense. Postępy biochemii 2023. https://doi.org/10.18388/pb.2021_503.
  2. Walendzik K, Kopcewicz M, Wiśniewska J, Opyd P, Machcińska-Zielińska S, Gawrońska-Kozak B. Dermal white adipose tissue development and metabolism: The role of transcription factor Foxn1. FASEB J. 2023 Oct;37(10):e23171. (doi: 10.1096/fj.202300873RR).
  3. Gawronska-Kozak, B.; Kopcewicz, M.; Machcinska-Zielinska, S.;Walendzik, K.; Wisniewska, J.; Drukała, J.;Wasniewski, T.; Rutkowska, J.; Malinowski, P.; Pulinski, M. Gender Differences in Post-Operative Human Skin. Biomedicines 2023, 11, 2653. (doi.org/10.3390/biomedicines11102653). 

2022

  1. Gawrońska-Kozak, Barbara; Walendzik, Katarzyna; Machcińska, Sylwia; Padzik, Artur; Kopcewicz, Marta; Wiśniewska, Joanna. Dermal white adipose tissue (dWAT) is regulated by Foxn1 and Hif‐1α during the early phase of skin wound healing. International Journal of Molecular Sciences 2022, 23(1): art. no 257 (1-22) (10.3390/ijms23010257).
  2. Machcińska, Sylwia; Walendzik, Katarzyna; Kopcewicz, Marta; Wiśniewska, Joanna; Rokka, Anne; Pääkkönen, Mirva; Słowińska, Mariola; Gawrońska-Kozak, Barbara. Hypoxia reveals a new function of Foxn1 in the keratinocyte antioxidant defense system. FASEB Journal 2022, 36(8): art. no e22436 (1-25) (10.1096/fj.202200249RR).
  3. Wiśniewska, Joanna; Słyszewska, Magda; Kopcewicz, Marta; Walendzik, Katarzyna; Machcińska, Sylwia; Stałanowska, Karolina; Gawrońska-Kozak, Barbara. Comparative studies on the effect of pig adipose-derived stem cells (pASCs) preconditioned with hypoxia or normoxia on skin wound healing in mice. Experimental Cell Research2022, 418(1): art. no 113263 (1-15) (1016/j.yexcr.2022.113263).

2021

  1. Bukowska, Joanna; Szóstek-Mioduchowska, Anna Z.; Kopcewicz, Marta; Walendzik, Katarzyna; Machcińska, Sylwia; Gawrońska-Kozak, Barbara. Adipose-derived stromal/stem cells from large animal models: from basic to applied science. Stem Cell Reviews and Reports 2021, 17: 719-738 (10.1007/s12015-020-10049-y).
  2. Bukowska, Joanna; Walendzik, Katarzyna; Kopcewicz, Marta; Cierniak, Patrycja; Gawrońska-Kozak, Barbara. Wnt signaling and the transcription factor Foxn1 contribute to cutaneous wound repair in mice. Connective Tissue Research 2021, 62(2): 238-248 (10.1080/03008207.2019.1688314).
  3. Gawrońska-Kozak, Barbara; Kur-Piotrowska, Anna; Wiśniewska, Joanna; Kpcewicz, Marta. Molekularne mechanizmy działania czynnika transkrypcyjnego FOXN1 w skórze []. Postępy Higieny i Medycyny Doświadczalnej 2021, 75: 573-583 (10.2478/ahem-2021-0028).
  4. Machcińska, Sylwia; Kopcewicz, Marta; Bukowska, Joanna; Walendzik, Katarzyna; Gawrońska-Kozak, Barbara. Impairment of the Hif‐1α regulatory pathway in Foxn1‐deficient (Foxn1−/−) mice affects the skin wound healing process. FASEB Journal 2021, 35(2): art. no e21289 (1-22) (10.1096/fj.202001907R).
  5. Słowińska, Mariola; Pardyak, Laura; Liszewska, Ewa; Judycka, Sylwia; Bukowska, Joanna; Dietrich, Mariola A.; Paukszto, Łukasz; Jastrzębski, Jan; Kozłowski, Krzysztof; Kowalczyk, Artur; Jankowski, Jan; Bilińska, Barbara; Ciereszko, Andrzej. Characterization and biological role of cysteine-rich venom protein belonging to CRISPs from turkey seminal plasma. Biology of Reproduction 2021, 104(6): 1302-1321 (10.1093/biolre/ioab032).
  6. van de Vyver, Mari; Boodhoo, Kiara; Fraazier, Trivia; Hamel, Katie; Kopcewicz, Marta; Levi, Benjamin; Maartens, Michelle; Machcińska, Sylwia; Nunez, Johanna; Pagani, Chase; Rogers, Emma; Walendzik, Katarzyna; Wiśniewska, Joanna; Gawrońska-Kozak, Barbara; Gimble, Jeffrey. Histology scoring system for murine cutaneous wounds. Stem Cells and Development 2021, 30(23): 1141-1152 (10.1089/scd.2021.0124).
  7. Wiśniewska, Joanna; Sadowska, Agnieszka; Wójtowicz, Anna; Słyszewska, Magda; Szóstek-Mioduchowska, Anna Z. Perspective on stem cell therapy in organ fibrosis: animal models and human studies. Life-Basel 2021, 11(10): art. no 1068 (1-42) (10.3390/life11101068).
  8. Wiśniewska, Joanna; Słyszewska, Magda; Stałanowska, Karolina; Walendzik, Katarzyna; Kopcewicz, Marta; Machcińska, Sylwia; Gawrońska-Kozak, Barbara. Effect of pig-adipose-derived stem cells’ conditioned media on skin wound-healing characteristics in vitro. International Journal of Molecular Sciences 2021, 22(11): art. no 5469 (1-19) (10.3390/ijms22115469).

2020

  1. Amaral, Ana; Fernandes, Carina; Morazzo, Sofia; Rebordão, Maria R.; Szóstek-Mioduchowska, Anna Z.; Łukasik, Karolina; Gawrońska-Kozak, Barbara; Telo da Gama, Luís; Skarżyński, Dariusz J.; Ferreira-Dias, Graça. The inhibition of cathepsin G on endometrial explants with endometrosis in the mare. Frontiers in Veterinary Science 2020, 7: art. no 582211 (1-11) (10.3389/fvets.2020.582211).
  2. Amaral, Ana; Fernandes, Carina; Rebordão, Maria R.; Szóstek-Mioduchowska, Anna Z.; Łukasik, Karolina; Gawrońska-Kozak, Barbara; da Gama, Luís Telo; Skarżyński, Dariusz J.; Ferreira-Dias, Graça. The in vitro inhibitory effect of sivelestat on elastase induced collagen and metallopeptidase expression in equine endometrium. Animals 2020, 10(5): art. no 863 (1-17) (10.3390/ani10050863).
  3. Bender, Robert; McCarthy, Michelle; Brown, Theodore; Bukowska, Joanna; Smith, Stanley; Abbott, Rosalyn D.; Kaplan, David L.; Williams, Christopher; Wade, James W.; Alarcon, Andrea; Wu, Xiying; Lau, Frank; Gimble, Jeffrey M.; Frazier, Trivia. Human adipose derived cells in two- and three-dimensional cultures: functional validation of an In vitro fat construct. Stem Cells International 2020, 2020: art. no 4242130 (1-14) (10.1155/2020/4242130).
  4. Bukowska, Joanna; Słowińska, Mariola; Cierniak, Patrycja; Kopcewicz, Marta; Walendzik, Katarzyna; Frazier, Trivia; Gawrońska-Kozak, Barbara. The effect of hypoxia on the proteomic signature of pig adipose-derived stromal/stem cells (pASCs). Scientific Reports 2020, 10: art. no 20035 (1-13) (10.1038/s41598-020-76796-7).
  5. Bukowska, Joanna; Uquillas, Andrea Alarcon; Wu, Xiying; Fraazier, Trivia; Walendzik, Katarzyna; Vanek, Mikaela; Gaupp, Dina; Bunnell, Bruce A.; Kosnik, Paul; Mehrara, Babak; Katz, Adam J.; Gawrońska-Kozak, Barbara; Gimble, Jeffrey. Safety and efficacy of human adipose-derived stromal/stem cell therapy in an immunocompetent murine pressure ulcer model. Stem Cells and Development 2020, 29(7): 440-451 (10.1089/scd.2019.0244).
  6. Bukowska, Joanna; Uquillas, Andrea Alarcon; Wu, Xiying; Fraazier, Trivia; Walendzik, Katarzyna; Vanek, Mikaela; Gaupp, Dina; Bunnell, Bruce A.; Kosnik, Paul; Mehrara, Babak; Katz, Adam J.; Gawrońska-Kozak, Barbara; Gimble, Jeffrey. Safety of human adipose stromal vascular fraction cells isolated with a closed system device in an immunocompetent murine pressure ulcer model. Stem Cells and Development 2020, 29(7): 452-461 (10.1089/scd.2019.0245).
  7. Gawrońska-Kozak, Barbara. Foxn1 control of skin function. Applied Sciences-Basel 2020, 10(16): art. no 5685 (1-12) (10.3390/app10165685).
  8. Kopcewicz, Marta; Walendzik, Katarzyna; Bukowska, Joanna; Kur-Piotrowska, Anna; Machcińska, Sylwia; Gimble, Jeffrey M.; Gawrońska-Kozak, Barbara. Cutaneous wound healing in aged, high fat diet-induced obese female or male C57BL/6 mice. Aging-US 2020, 12(8): 7066-7111 (10.18632/aging.103064).
  9. Słowińska, Mariola; Paukszto, Ł.; Jastrzębski, Jan; Bukowska, Joanna; Kozłowski, Krzysztof; Jankowski, Jan; Ciereszko, Andrzej. Transcriptome analysis of turkey (Meleagris gallopavo) reproductive tract revealed key pathways regulating spermatogenesis and post-testicular sperm maturation. Poultry Science 2020, 99(11): 6094-6118 (10.1016/j.psj.2020.07.031).
  10. Walendzik, Katarzyna; Bukowska, Joanna; Kopcewicz, Marta; Machcińska, Sylwia; Gimble, Jeffrey M.; Gawrońska-Kozak, Barbara. Age, diet and epidermal signaling modulate dermal fibroblasts’ adipogenic potential. International Journal of Molecular Sciences 2020, 21(23): art. no 8955 (1-19) (10.3390/ijms21238955).
  11. Walendzik, Katarzyna; Kopcewicz, Marta; Bukowska, Joanna; Panasiewicz, Grzegorz; Szafrańska, Bożena; Gawrońska-Kozak, Barbara. The transcription factor Foxn1 regulates skin adipogenesis and affects susceptibility to diet-induced obesity. Journal of Investigative Dermatology 2020, 140(6): 1166-1175.e9 (10.1016/j.jid.2019.11.010).

2019

  1. Cowper, Mathew; Frazier, Trivia; Wu, Xiying; Curley, J. Lowry; Ma, Michelle H.; Mohiuddin, Omair A.; Dietrich, Marilyn; McCarthy, Michelle; Bukowska, Joanna; Gimble, Jeffrey M. Human platelet lysate as a functional substitute for fetal bovine serum in the culture of human adipose derived stromal/stem cells. Cells 2019, 8(7): art. no 724 (1-13) (10.3390/cells8070724).
  2. Słowińska, Mariola; Hejmej, Anna; Bukowska, Joanna; Liszewska, Ewa; Bilińska, Barbara; Hliwa, Piotr; Kozłowski, Krzysztof; Jankowski, Jan; Ciereszko, Andrzej. Expression and secretion of albumin in male turkey (Meleagris gallopavo) reproductive tract in relation to yellow semen syndrome. Poultry Science 2019, 98(4): 1872-1882 (10.3382/ps/pey490).

2018

  1. Bukowska, Joanna; Frazier, Trivia P.; Smith, Stanley; Brown, Theodore A.; Bender, Robert; McCarthy, Michelle E.; Wu, Xiying; Bunnell, Bruce A.; Gimble, Jeffrey M. Bone marrow adipocyte developmental origin and biology. Current Osteoporosis Reports 2018, 16(3): 312-319 (10.1007/s11914-018-0442-z).
  2. Bukowska, Joanna; Kopcewicz, Marta; Kur-Piotrowska, Anna; Szóstek-Mioduchowska, Anna Z.; Walendzik, Katarzyna; Gawrońska-Kozak, Barbara. Effect of TGFβ1, TGFβ3 and keratinocyte conditioned media on functional characteristics of dermal fibroblasts derived from reparative (Balb/c) and regenerative (Foxn1 deficient, nude) mouse models. Cell and Tissue Research 2018, 374(1): 149-163 (10.1007/s00441-018-2836-8).
  3. Bukowska, Joanna; Kopcewicz, Marta; Walendzik, Katarzyna; Gawrońska-Kozak, Barbara. Foxn1 in skin development, homeostasis and wound healing. International Journal of Molecular Sciences 2018, 19(7): art. no 1956 (1-28) (10.3390/ijms19071956).
  4. Gawrońska-Kozak, Barbara; Bukowska, Joanna; Wu, Xiying; Strong, Amy L.; Frazier, Trivia P.; Bunnell, Bruce A.; Gimble, Jeffrey M. Contribution of adipose-derived cells to skin wound healing. W: Wound healing: stem cells repair and restorations, basic and clinical aspects. Ed.: Turksen, Kursad. John Wiley & Sons, Inc., Hoboken, NJ, USA 2018 (ISBN 9781119282488), Chapter 7: 89-101 (10.1002/9781119282518.ch7).
  5. Kur-Piotrowska, Anna; Bukowska, Joanna; Kopcewicz, Marta; Dietrich, Mariola A.; Nynca, Joanna; Słowińska, Mariola; Gawrońska-Kozak, Barbara. Foxn1 expression in keratinocytes is stimulated by hypoxia: further evidence of its role in skin wound healing. Scientific Reports 2018, 8(1): art. no 5425 (1-14) (10.1038/s41598-018-23794-5).
  6. McCarthy, Michelle E.; Brown, Theodore A.; Bukowska, Joanna; Bunnell, Bruce A.; Frazier, Trivia P.; Wu, Xiying; Gimble, Jeffrey M. Therapeutic applications for adipose-derived stem cells in wound healing and tissue engineering. Current Stem Cell Reports 2018, 4(2): 127-137 (10.1007/s40778-018-0125-9).

2017

  1. Chu, Dinh-Toi; Gawrońska-Kozak, Barbara. Brown and brite adipocytes: Same function, but different origin and response. Biochimie 2017, 138: 102-105 (10.1016/j.biochi.2017.04.017).
  2. Gawrońska-Kozak, Barbara; Bukowska, Joanna. Animal models of skin regeneration. W: Animal Models for the Study of Human Disease. Ed.: Conn, P. Michael. Elsevier, London 2017 (ISBN 978-0-12-809468-6), Chapter 14: 343-356 (10.1016/B978-0-12-809468-6.00014-0).
  3. Kopcewicz, Marta; Kur-Piotrowska, Anna; Bukowska, Joanna; Gimble, Jeffrey M.; Gawrońska-Kozak, Barbara. Foxn1 and Mmp-9 expression in intact skin and during excisional wound repair in young, adult and old C57Bl/6 mice. Wound Repair and Regeneration 2017, 25(2): 248-259 (10.1111/wrr.12524).
  4. Kur-Piotrowska, Anna; Kopcewicz, Marta; Kozak, Leslie P.; Sachadyn, Paweł; Grabowska, Anna; Gawrońska-Kozak, Barbara. Neotenic phenomenon in gene expression in the skin of Foxn1- deficient (nude) mice – a projection for regenerative skin wound healing. BMC Genomics 2017, 18(1): art. no 56 (1-15) (10.1186/s12864-016-3401-z).

2016

  1. Floyd, Z. Elizabeth; Gawrońska-Kozak, Barbara; Tam, Charmaine S.; Gimble, Jeffrey M. Mechanisms of metabolism, aging and obesity. Biochimie 2016, 124: 1-2 (10.1016/j.biochi.2016.03.005).
  2. Gawrońska-Kozak, Barbara; Grabowska, Anna; Kur-Piotrowska, Anna; Kopcewicz, Marta. Foxn1 transcription factor regulates wound healing of skin through promoting epithelial-mesenchymal transition. PLoS ONE 2016, 11(3): art. no e0150635 (1-21) (10.1371/journal.pone.0150635).
  3. Giménez-Bastida, Juan A.; Surma, Magdalena; Bukowska, Joanna. In vitro study of the exposition of human myofibroblasts of colon CCD-18Co to perfluorooctanoic acid (PFOA). W: Perfluorooctanoic Acid (PFOA): Global Occurrence, Exposure and Health Effects. Ed.: Hampton, Eva. Nova Science Publisher 2016 (ISBN 978-163484913-5), Chapter 2: 33-51.

2015

  1. Strong, Amy L.; Bowles, Annie C.; MacCrimmon, Connor P.; Frazier, Trivia P.; Lee, Stephen J.; Wu, Xiying; Katz, Adam J.; Gawrońska-Kozak, Barbara; Bunnell, Bruce A.; Gimble, Jeffrey M. Adipose stromal cells repair pressure ulcers in both young and elderly mice: potential role of adipogenesis in skin repair. Stem Cells Translational Medicine 2015, 4(6): 632-642 (10.5966/sctm.2014-0235).
  2. Strong, Amy L.; Bowles, Annie C.; MacCrimmon, Connor P.; Lee, Stephen J.; Frazier, Trivia P.; Katz, Adam J.; Gawrońska-Kozak, Barbara; Bunnell, Bruce A.; Gimble, Jeffrey M. Characterization of a murine pressure ulcer model to assess efficacy of adipose-derived stromal cells. Plastic and Reconstructive Surgery 2015, 3(3): art. no e334 (1-9) (10.1097/GOX.0000000000000260).

2014

  1. Chu, Dinh-Toi; Malinowska, Elżbieta; Gawrońska-Kozak, Barbara; Kozak, Leslie P. Expression of adipocyte biomarkers in a primary cell culture models reflects preweaning adipobiology. Journal of Biological Chemistry 2014, 289(26): 18478-18488 (10.1074/jbc.M114.555821).
  2. Gawrońska-Kozak, Barbara. Preparation and differentiation of mesenchymal stem cells from ears of adult mice. Methods in Enzymology 2014, 538: 1-13 (10.1016/B978-0-12-800280-3.00001-3).
  3. Gawrońska-Kozak, Barbara; Grabowska, Anna; Kopcewicz, Marta; Kur, Anna. Animal models of skin regeneration. Reproductive Biology 2014, 14(1): 61-67 (10.1016/j.repbio.2014.01.004).
  4. Gawrońska-Kozak, Barbara; Staszkiewicz, Jarosław; Gimble, Jeffrey M.; Kirk-Ballard, Heather. Recruitment of fat cell precursors during high fat diet in C57BL/6J mice is fat depot specific. Obesity 2014, 22(4): 1091-1102 (10.1002/oby.20671).

2013

  1. Gao, Ru; Rim, Jong S.; Strickler, Karen L.; Barnes, Christian W.; Harkins, Lettie L.; Staszkiewicz, Jarosław; Gimble, Jeffery M.; Gawrońska-Kozak, Barbara; Leno, Gregory H.; Eilertsen, Kenneth J. Reprogramming mouse ear mesenchymal stem cells (EMSC) expressing the Dlk1-Dio3 imprinted gene cluster. Stem Cell Discovery 2013, 3(1): 64-71 (10.4236/scd.2013.31010).
  2. Gawrońska-Kozak, Barbara; Kirk-Ballard, Heather. Cyclosporin A reduces matrix metalloproteinases and collagen expression in dermal fibroblasts from regenerative FOXN1 deficient (nude) mice. Fibrogenesis & Tissue Repair 2013, 6(1): art. no 7 (1-11) (10.1186/1755-1536-6-7).

2012

  1. Staszkiewicz J, Gimble JM, Dietrich MA, Gawronska-Kozak B. Diet-induced obesity in stem cell antigen-1 KO mice. Stem Cells Dev. 2012 Jan 20;21(2):249-59. doi: 10.1089/scd.2010.0507. Epub 2011 Jun 1.

2011

  1. Gawronska-Kozak B. Scarless skin wound healing in FOXN1 deficient (nude) mice is associated with distinctive matrix metalloproteinase expression. Matrix Biol. 2011 May;30(4):290-300. doi: 10.1016/j.matbio.2011.04.004. Epub 2011 Apr 22.

2010

  1. Tang T, Zhang J, Yin J, Staszkiewicz J, Gawronska-Kozak B, Jung DY, Ko HJ, Ong H, Kim JK, Mynatt R, Martin RJ, Keenan M, Gao Z, Ye J. Uncoupling of inflammation and insulin resistance by NF-kappaB in transgenic mice through elevated energy expenditure. J Biol Chem. 2010 Feb 12;285(7):4637-44. doi: 10.1074/jbc.M109.068007. Epub 2009 Dec 17.
  2. Staszkiewicz J, Frazier TP, Rowan BG, Bunnell BA, Chiu ES, Gimble JM, Gawronska-Kozak B. Cell growth characteristics, differentiation frequency, and immunophenotype of adult ear mesenchymal stem cells. Stem Cells Dev. 2010 Jan;19(1):83-92. doi: 10.1089/scd.2009.0051.

2009

  1. Staszkiewicz J, Gimble J, Cain C, Dietrich M, Burk D, Kirk-Ballard H, Gawronska-Kozak B. Flow cytometric and immunohistochemical detection of in vivo BrdU-labeled cells in mouse fat depots. Biochem Biophys Res Commun. 2009 Jan 16;378(3):539-44. doi: 10.1016/j.bbrc.2008.11.092. Epub 2008 Dec 3.

2008

  1. Staszkiewicz J, Gimble JM, Manuel JA, Gawronska-Kozak B. IFATS collection: Stem cell antigen-1-positive ear mesenchymal stem cells display enhanced adipogenic potential. Stem Cells. 2008 Oct;26(10):2666-73. doi: 10.1634/stemcells.2008-0270. Epub 2008 Jul 3.

2007

  1. Trevaskis JL, Gawronska-Kozak B, Sutton GM, McNeil M, Stephens JM, Smith SR, Butler AA. Role of adiponectin and inflammation in insulin resistance of Mc3r and Mc4r knockout mice. Obesity (Silver Spring). 2007 Nov;15(11):2664-72. doi: 10.1038/oby.2007.318.
  2. Gawronska-Kozak B, Manuel JA, Prpic V. Ear mesenchymal stem cells (EMSC) can differentiate into spontaneously contracting muscle cells. J Cell Biochem. 2007 Sep 1;102(1):122-35. doi: 10.1002/jcb.21286.
  3. Gao Z, Wang Z, Zhang X, Butler AA, Zuberi A, Gawronska-Kozak B, Lefevre M, York D, Ravussin E, Berthoud HR, McGuinness O, Cefalu WT, Ye J. Inactivation of PKCtheta leads to increased susceptibility to obesity and dietary insulin resistance in mice. Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E84-91. doi: 10.1152/ajpendo.00178.2006. Epub 2006 Aug 8

2006

  1. Manuel JA, Gawronska-Kozak B. Matrix metalloproteinase 9 (MMP-9) is upregulated during scarless wound healing in athymic nude mice. Matrix Biol. 2006 Oct;25(8):505-14. doi: 10.1016/j.matbio.2006.07.008. Epub 2006 Aug 16.
  2. Gawronska-Kozak B, Bogacki M, Rim JS, Monroe WT, Manuel JA. Scarless skin repair in immunodeficient mice. Wound Repair Regen. 2006 May-Jun;14(3):265-76. doi: 10.1111/j.1743-6109.2006.00121.x.

2005

  1. Rim JS, Mynatt RL, Gawronska-Kozak B. Mesenchymal stem cells from the outer ear: a novel adult stem cell model system for the study of adipogenesis. FASEB J. 2005 Jul;19(9):1205-7. doi: 10.1096/fj.04-3204fje. Epub 2005 Apr 27.

2004

  1. Gawronska-Kozak B. Regeneration in the ears of immunodeficient mice: identification and lineage analysis of mesenchymal stem cells. Tissue Eng. 2004 Jul-Aug;10(7-8):1251-65. doi: 10.1089/ten.2004.10.1251.
  2. Rim JS, Xue B, Gawronska-Kozak B, Kozak LP. Sequestration of thermogenic transcription factors in the cytoplasm during development of brown adipose tissue. J Biol Chem. 2004 Jun 11;279(24):25916-26. doi: 10.1074/jbc.M402102200. Epub 2004 Apr 8.

2003

  1. Smith SR, Gawronska-Kozak B, Janderová L, Nguyen T, Murrell A, Stephens JM, Mynatt RL. Agouti expression in human adipose tissue: functional consequences and increased expression in type 2 diabetes. Diabetes. 2003 Dec;52(12):2914-22. doi: 10.2337/diabetes.52.12.2914.