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Achievements PoMD

  1. Participation in the development of simple and accurate method of assessing insulin sensitivity, FLAIS (Fasting Laboratory Assessment of Insulin Sensitivity), which allows to identify insulin resistance even in the population without overt metabolic disturbances.
  2. Demonstration of altered adipose tissue and skeletal muscle expression of thyroid hormone-related genes in obesity, which indicates a decreased tissue thyroid hormone action.
  3. Demonstration that transcription faction RUNX1 in skeletal muscle is associated with insulin sensitivity mainly through its effect on myogenesis. These data indicate that myogenic/regenerative potential of adult skeletal muscle may be an important determinant of insulin action.
  4. Demonstration weight loss in subjects with uncomplicated obesity is not associated with a reduction in adipose tissue inflammation, but excessive lipolysis may prevent an improvement in insulin sensitivity during weight loss.

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Current projects PoMD

  1. The search for the novel mechanisms linking intracellular calcium flux regulation with insulin sensitivity response to regular physical exercise – grant from National Science Centre (NCN nr 2021/41/B/NZ7/03948).

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Equipment and applied methods B&PoHR

Research methods and equipment

Cell and molecular biology methods:

  • Isolation and culture of primary cells,
  • Work with cell lines:
    • culture of adherent and suspension cells,
    • transfection of cells,
    • lentiviral transduction of cells,
  • Isolation of DNA and RNA from tissues, cultured cells and body fluids,
  • Gene expression analysis by real-time RT PCR,
  • Analysis of gene polymorphisms by DNA sequencing,
  • Western-blot analysis of protein expression;,
  • FACS,
  • Detection of specific DNA fragments using Southern blot hybridization.

Equipment:

  • HERASAFE KS ThermoScientific laminar flow cell culture chamber,
  • cell culture incubators,
  • RealTime PCR Applied Biosystems Step One Plus,
  • Pegasus 4D, GCxGC TOF MS,
  • IN Cell Analyzer 2000HS,
  • Olympus CKX41 brightfield inverted microscope,
  • Tecan infinite m200pro plate reader,
  • DNA/RNA and protein electrophoresis apparatus with comb kit,
  • electro-transfer unit,
  • electrophoresis apparatus with comb set,
  • CASA system for computerised semen analysis,
  • autoclave,
  • ultrasonic cleaner Elma Elmasonic S 100H,
  • dry sterilisation oven,
  • UltraTurax homogeniser,
  • ThermoScientific STR8 centrifuge with cooling and variable rotors for 1.5, 2.0, 15 and 50 ml tubes,
  • laboratory centrifuge with cooling.

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Publications B&PoHR

2024

  1. Krentowska, Anna; Ponikwicka-Tyszko, Donata; Łebkowska, Agnieszka; Adamska, Agnieszka; Sztachelska, Maria; Milewska, Gabiela; Hryniewicka, Justyna; Wołczyński, Sławomir; Kowalska, Irina. Serum expression levels of selected microRNAs and their association with glucose metabolism in young women with polycystic ovary syndrome. Polish Archives of Internal Medicine – Polskie Archiwum Medycyny Wewnętrznej 2024, 134(1): art. no 16637 (1-5) (10.20452/pamw.16637).
  2. Milewska,Gabriela; Ponikwicka–Tyszko, Donata; Bernaczyk, Piotr; Lupu, Oana; Szamatowicz, Michał; Sztachelska, Maria; Pilaszewicz-Puza, Agata; Koda, Mariusz; Bielawski, Tomasz; Zbucka-Kretowska, Monika; Pawelczyk, Adam; Tomaszewski, Jakub; Li, Xiangdong; Huhtaniemi, Ilpo; Wołczyński, Slawomir; Rahman, Nafis A. Functional evidence for two distinct mechanisms of action of progesterone and selective progesterone receptor modulator on uterine leiomyomas. Fertility and Sterility 2024, 122(2): 341-351 (10.1016/j.fertnstert.2024.02.046).
  3. Puławska-Moon, Kamila; Ponikwicka-Tyszko, Donata; Lebiedzińska, Weronika; Pilaszewicz-Puza, Agata; Bernaczyk, Piotr; Koda, Mariusz; Lupu, Oana; Milewska, Gabriela; Huang, Chen-Che Jeff; Zheng, Huifei; Schiele, Phillip; Na, Il-Kang; Frentsch, Marco; Li, Xiangdong; Toppari, Jorma; Wołczyński, Slawomir; Coelingh Bennink, Herjan J. T.; Huhtaniemi, Ilpo; Rahman, Nafis A. Novel ectopic expression of zona pellucida 3 glycoprotein in lung cancer promotes tumor growth. International Journal of Cancer 2024, 155(10): 1846-1857 (10.1002/ijc.35098).
  4. Szucio, Weronika; Bernaczyk, Piotr; Ponikwicka-Tyszko, Donata; Milewska, Gabriela; Pawelczyk, Adam; Wołczyński, Sławomir; Rahman, Nafis A. Progesterone signaling in uterine leiomyoma biology: Implications for potential targeted therapy. Advances in Medical Sciences 2024, 69(1): 21-28 (10.1016/j.advms.2024.01.001).

2023

  1. Kamińska, Joanna; Koper-Lenkiewicz, Olga M.; Ponikwicka-Tyszko, Donata; Lebiedzińska, Weronika; Palak, Ewelina; Sztachelska, Maria; Bernaczyk, Piotr; Dorf, Justyna; Guzińska-Ustymowicz, Katarzyna; Zaręba, Konrad; Wołczyński, Sławomir; Rahman, Nafis A.; Dymicka-Piekarska, Violetta. New Insights on the Progesterone (P4) and PGRMC1/NENF Complex Interactions in Colorectal Cancer Progression. Cancers 2023, 15(20): art. no 5074 (1-21) (10.3390/cancers15205074).
  2. Liu, Yajing; Zhang, Shanshan; Chen, Li; Huang, Xuan; Wang, Mingming; Ponikwicka-Tyszko, Donata; Rahman, Nafis A.; Wołczyński, Sławomir; Yao, Bing; Li, Xiangdong. The molecular mechanism of miR-96-5p in the pathogenesis and treatment of polycystic ovary syndrome. Translational Research 2023, 256: 1-13 (10.1016/j.trsl.2022.12.007).
  3. Palak, Ewelina; Lebiedzińska, Weronika; Lupu, Oana; Puławska, Kamila; Anisimowicz, Sławomir; Mieczkowska, Aleksandra N.; Sztachelska, Maria; Niklińska, Gabriella N.; Milewska, Gabriela; Łukasiewicz, Monika; Ponikwicka-Tyszko, Donata; Huhtaniemi, Ilpo; Wołczyński, Sławomir. Molecular insights underlying the adverse effects of bisphenol A on gonadal somatic cells’ steroidogenic activity. Reproductive Biology 2023, 23(2): art. no 100766 (1-12) (10.1016/j.repbio.2023.100766).
  4. Zhang, Shanshan; Liu, Yajing; Wang, Mingming; Ponikwicka-Tyszko, Donata; Ma, Wenqiang; Krentowska, Anna; Kowalska, Irina; Huhtaniemi, Ilpo; Wołczyński, Slawomir; Rahman, Nafis A.; Li, Xiangdong. Role and mechanism of miR-335-5p in the pathogenesis and treatment of polycystic ovary syndrome. Translational Research 2023, 252: 64-78 (10.1016/j.trsl.2022.07.007).

2022

  1. Nowak, Karolina; Jabłońska, Ewa; Garley, Marzena; Iwaniuk, Agnieszka; Radziwon, Piotr; Wołczyński, Sławomir; Ratajczak-Wrona, Wioletta. Investigation of estrogen-like effects of parabens on human neutrophils. Environmental Research 2022, 214(Part 1): art. no 113893 (1-12) (10.1016/j.envres.2022.113893).
  2. Omeljaniuk, Wioleta J.; Charkiewicz, Angelika E.; Garley, Marzena; Ratajczak-Wrona, Wioletta; Czerniecki, Jan; Jabłońska, Ewa; Cechowska-Pasko, Marzanna; Miltyk, Wojciech. Bisphenol A: potential factor of miscarriage in women in the context of the phenomenon of neutrophil extracellular traps. Archivum Immunologiae et Therapiae Experimentalis 2022, 70: art. no 24 (1-10) (10.1007/s00005-022-00661-w).
  3. Puławska, Kamila; Ponikwicka-Tyszko, Donata; Lebiedzińska, Weronika; Guod, Peilan; Bernaczyk, Piotr; Pilaszewicz-Puza, Agata; Li, Xiangdong; Chruściel, Marcin; Lupu, Oana; Leskinen, Sini; Makela, Juho-Antti; Toppari, Jorma; Wołczyński, Slawomir; Coelingh Bennink, Herjan J.T.; Huhtaniemi, Ilpo; Rahman, Nafis A. Novel expression of zona pellucida 3 protein in normal testis; potential functional implications. Molecular and Cellular Endocrinology 2022, 539: art. no 111502 (1-10) (10.1016/j.mce.2021.111502).
  4. Sztachelska, Maria; Ponikwicka-Tyszko, Donata; Martínez-Rodrigo, Lydia; Bernaczyk, Piotr; Palak, Ewelina; Półchłopek, Weronika; Bielawski, Tomasz; Wołczyński, Sławomir. Functional implications of estrogen and progesterone receptors expression in adenomyosis, potential targets for endocrinological therapy. Journal of Clinical Medicine 2022, 11(15): art. no 4407 (1-16) (10.3390/jcm11154407).

2021

  1. Komarowska, Marta D.; Grubczak, Kamil; Czerniecki, Jan; Hermanowicz, Adam; Hermanowicz, Justyna M.; Dębek, Wojciech; Matuszczak, Ewa. Identification of the bisphenol A (BPA) and the two analogues BPS and BPF in cryptorchidism. Frontiers in Endocrinology 2021, 12: art. no 694669 (1-9) (10.3389/fendo.2021.694669).
  2. Łukasiewicz, Monika; Czerniecki, Jan; Ponikwicka-Tyszko, Donata; Sztachelska, Maria; Hryniewicka, Marta; Nalewajko-Sieliwonik, Edyta; Wiczkowski, Wiesław; Banaszewska, Beata; Milewski, Robert; Toppari, Jorma; Huhtaniemi, Ilpo; Rahman, Nafis A.; Wołczyński, Sławomir. Placenta is capable of protecting the male fetus from exposure to environmental bisphenol A. Exposure and Health 2021, 12: 1-14 (10.1007/s12403-020-00358-5).
  3. Palak, Ewelina; Lebiedzińska, Weronika; Anisimowicz, Sławomir; Sztachelska, Maria; Pierzyński, Piotr; Wiczkowski, Wiesław; Żelazowska-Rutkowska, Beata; Niklińska, Gabriella N.; Ponikwicka-Tyszko, Donata; Wołczyński, Sławomir. The association between bisphenol A, steroid hormones, and selected microRNAs levels in seminal plasma of men with Infertility. Journal of Clinical Medicine 2021, 10(24): art. no 5945 (1-11) (10.3390/jcm10245945).
  4. Ratajczak-Wrona, Wioletta; Garley, Marzena; Rusak, Małgorzata; Nowak, Karolina; Czerniecki, Jan; Wołosewicz, Katarzyna; Dąbrowska, Milena; Wołczyński, Sławomir; Radziwoń, Piotr; Jablońska, Ewa. Sex-dependent dysregulation of human neutrophils responses​ by bisphenol A. Environmental Health 2021, 20(1): art. no 5 (1-18) (10.21203/rs.3.rs-26406/v1).

2020

  1. Ponikwicka-Tyszko, Donata; Chruściel, Marcin; Puławska, Kamila; Bernaczyk, Piotr; Sztachelska, Maria; Guo, Peilan; Li, Xiangdong; Toppari, Jorma; Huhtaniemi, Ilpo T.; Wołczyński, Sławomir; Rahman, Nafis A. Mifepristone treatment promotes testicular leydig cell tumor progression in transgenic mice. Cancers 2020, 12(11): art. no 3263 (1-18) (10.3390/cancers12113263).

2019

  1. Chruściel, Marcin; Ponikwicka-Tyszko, Donata; Wołczyński, Sławomir; Huhtaniemi, Ilpo; Rahman, Nafis A. Extragonadal FSHR expression and function – Is it real?. Frontiers in Endocrinology 2019, 10: art. no 32 (1-13) (doi: 10.3389/fendo.2019.00032).
  2. Kowalczyk-Zięba, Ilona; Wocławek-Potocka, Izabela; Waśniewski, Tomasz; Boruszewska, Dorota; Grycmacher, Katarzyna; Sinderewicz, Emilia; Staszkiewicz, Joanna; Wołczyński, Sławomir. LPAR2 and LPAR4 are the main receptors responsible for LPA actions in ovarian endometriotic cysts. Reproductive Sciences 2019, 26(1): 139-150 (doi: 10.1177/1933719118766263).
  3. Liu, Mei; Du, Yaqi; Li, Haiwen; Wang, Li; Ponikwicka-Tyszko, Donata; Lebiedzińska, Weronika; Pilaszewicz-Puza, Agata; Liu, Huijiao; Zhou, Lijun; Fan, Hanlu; Wang, Mingming; You, Hua; Wolczyński, Sławomir; Rahman, Nafis; Guo, Yang-Dong; Li, Xiangdong. Cyanidin-3-o-glucoside pharmacologically inhibits tumorigenesis via estrogen receptor β in melanoma mice. Frontiers in Oncology 2019, 9: art. no 1110 (1-18) (doi: 10.3389/fonc.2019.01110).
  4. Ponikwicka-Tyszko, Donata; Chruściel, Marcin; Stelmaszewska, Joanna; Bernaczyk, Piotr; Chruściel, Paulina; Sztachelska, Maria; Scheinin, Mika; Bidziński, Mariusz; Szamatowicz, Jacek; Huhtaniemi, Ilpo T.; Wolczynski, Slawomir; Rahman, Nafis A. Molecular mechanisms underlying mifepristone’s agonistic action on ovarian cancer progression. EBioMedicine 2019, 47: 170-183 (doi: 10.1016/j.ebiom.2019.08.035).
  5. Puławska, Kamila; Doroszko, Milena; Chruściel, Marcin; Ponikwicka-Tyszko, Donata; Wołczyński, Slawomir; Toppari, Jorma; Huhtaniemi, Ilpo; Rahman, Nafis A. Mouse models of adrenal tumors responsive to gonadotropin-releasing hormone and gonadotropins. Current Opinion in Endocrine and Metabolic Research 2019, 8: 189-194 (doi: 10.1016/j.coemr.2019.08.014).
  6. Ratajczak-Wrona, Wioletta; Nowak, Karolina; Garley, Marzena; Grubczak, Kamil; Dąbrowska, Dorota; Iwaniuka, Agnieszka; Wilk, Sara; Moniuszko, Marcin; Czerniecki, Jan; Wołczyński, Sławomir; Jablońska, Ewa. Expression of serine proteases in neutrophils from women and men: regulation by endocrine disruptor bisphenol A. Environmental Toxicology and Pharmacology 2019, 71: art. no 103212 (1-10) (doi: 10.1016/j.etap.2019.103212).
  7. Sztachelska, Maria; Ponikwicka-Tyszko, Donata; Sokołowska, Gabriela; Anisimowicz, Sławomir; Czerniecki, Jan; Lebiedzińska, Weronika; Zbucka-Kretowska, Monika; Zygmunt, Marek; Wołczyński, Sławomir; Pierzyński, Piotr. Oxytocin antagonism reverses the effects of high estrogen levels and oxytocin on decidualization and cyclooxygenase activity in endometrial tissues. Reproductive BioMedicine Online 2019, 39(5): 737-744 (doi: 10.1016/j.rbmo.2019.06.002).
  8. Zbucka-Krętowska, Monika; Łazarek, Urszula; Miltyk, Wojciech; Sidorkiewicz, Iwona; Pierzyński, Piotr; Milewski, Robert; Wołczyński, Sławomir; Czerniecki, Jan. Simultaneous analysis of bisphenol A fractions in maternal and fetal compartments in early second trimester of pregnancy. Journal of Perinatal Medicine 2019, 47(7): 765-770 (doi: 10.1515/jpm-2019-0040).

2018

  1. Huhtaniemi, Ilpo; Hovatta, Outi; La Marca, Antonio; Livera, Gabriel; Monniaux, Danielle; Persani, Luca; Heddar, Abdelkader; Jarząbek, Katarzyna; Laisk-Podar, Triin; Salumets, Andres; Tapanainen, Juha S.; Veitia, Reiner A.; Visser, Jenny A.; Wieacker, Peter; Wołczyński, Sławomir; Misrahi, Micheline. Advances in the molecular pathophysiology, genetics, and treatment of primary ovarian insufficiency. Trends in Endocrinology and Metabolism 2018, 29(6): 400-419 (doi: 10.1016/j.tem.2018.03.010).
  2. Sidorkiewicz, Iwona; Czerniecki, Jan; Jarząbek, Katarzyna; Zbucka-Krętowska, Monika; Wołczyński, Sławomir. Cellular, transcriptomic and methylome effects of individual and combined exposure to BPA, BPF, BPS on mouse spermatocyte GC-2 cell line. Toxicology and Applied Pharmacology 2018, 359: 1-11 (doi: 10.1016/j.taap.2018.09.006).
  3. Siemieniuk, Magdalena; Sosnowska, Katarzyna; Czerniecki, Jan; Czyżewska, Urszula; Winnicka, Katarzyna; Tylicki, Adam. Oxythiamine improves antifungal activity of ketoconazole evaluated in canine Malassezia pachydermatis strains. Veterinary Dermatology 2018, 29(6): 476-e160 (doi: 10.1111/vde.12688).
  4. Zbucka-Kretowska, Monika; Charkiewicz, Karol; Czerniecki, Jan; Gościk, Joanna; Wołczyński, Sławomir; Laudański, Piotr. Amniotic fluid angiogenic and inflammatory factor profiling in foetal down syndrome. Fetal Diagnosis and Therapy 2018, 44: 44-50 (doi: 10.1159/000478260).

2017

  1. Jarząbek, Katarzyna; Mikucka-Niczyporuk, Agnieszka; Bielawski, Tomasz; Milewski, Robert; Kubiak, Jacek Z.; Wołczyński, Sławomir. Evaluation of steroid receptors mRNA fingerprints in two groups of normozoospermic patients: men from unexplained infertility couples vs. men from couples with tubal factor infertility. Open Journal of Obstetrics and Gynecology 2017, 7(3): 290-302 (doi: 10.4236/ojog.2017.73031).
  2. Sidorkiewicz, Iwona; Zaręba, Kamil; Wołczyński, Sławomir; Czerniecki, Jan. Endocrine-disrupting chemicals – Mechanisms of action on male reproductive system. Toxicology and Industrial Health 2017, 33(7): 601-609 (doi: 10.1177/0748233717695160).
  3. Sokołowska, Gabriela; Ponikwicka-Tyszko, Donata; Sztachelska, Maria; Wołczyński, Sławomir. Wpływ progesteronu i octanu uliprystalu na wzrost i rozwój mięśniaków macicy. W: Badania i Rozwój MłodychNaukowców w Polsce. Choroby nowotworowe. Ed. Nyćkowiak, Jędrzej; Leśny Jacek. Wydawnictwo Młodzi Naukowcy, Poznań 2017 (ISBN 978-83-65917-01-0), 99-104.

2016

  1. Milewski, Robert; Czerniecki, Jan; Kuczyńska, Agnieszka; Stankiewicz, Bożena; Kuczyński, Waldemar. Morphokinetic parameters as a source of information concerning embryo developmental and implantation potential. Ginekologia Polska 2016, 87(10): 677-684 (doi: 10.5603/GP.2016.0067).
  2. Ponikwicka-Tyszko, Donata; Chruściel, Marcin; Stelmaszewska, Joanna; Bernaczyk, Piotr; Sztachelska, Maria; Sidorkiewicz, Iwona; Doroszko, Milena; Tomaszewski, Jakub; Tapanainen, Juha S.; Huhtaniemi, Ilpo; Wołczyński, Sławomir; Rahman, Nafis A. Functional expression of FSH receptor in endometriotic lesions. Journal of Clinical Endocrinology & Metabolism 2016, 101(7): 2905-2914 (doi: 10.1210/jc.2016-1014).
  3. Stelmaszewska, Joanna; Chruściel, Marcin; Doroszko, Milena; Akerfelt, Malin; Ponikwicka-Tyszko, Donata; Nees, Matthias; Frentsch, Marco; Li, Xiangdong; Kero, Jukka; Huhtaniemi, Ilpo; Wołczyński, Sławomir; Rahman, Nafis A. Revisiting the expression and function of follicle-stimulation hormone receptor in human umbilical vein endothelial cells. Scientific Reports 2016, 6: art. no 37095 (1-12) (doi: 10.1038/srep37095).

2015

  1. Choi, Jin-Ho; Balasubramanian, Ravikumar; Lee, Phil H.; Shaw, Natalie D.; Hall, Janet E.; Plummer, Lacey; Buck, Cassandra L.; Kottler, Marie-Laure; Jarząbek, Katarzyna; Wołczyński, Sławomir; Quinton, Richard; Latronico, Ana C.; Dode, Catherine; Ogata, Tsutomu; Kim, Hyung-Goo; Layman, Lawrence C.; Gusella, James F.; Crowley, William F. J. Expanding the spectrum of founder mutations causing isolated gonadotropin-releasing hormone deficiency. Journal of Clinical Endocrinology & Metabolism 2015, 100(10): E1378-E1385 (doi: 10.1210/jc.2015-2262).
  2. Malinowski, Paweł; Milewski, Robert; Ziniewicz, Piotr; Milewska, Anna J.; Czerniecki, Jan; Więsak, Teresa; Morgan, Allen; Surowik, Dariusz; Wołczyński, Sławomir. Classification of patients treated for infertility using the IVF method. Studies in Logic, Grammar and Rhetoric 2015, 43(56): 49-59 (doi: 10.1515/slgr-2015-0041).
  3. Mannelli, Chiara; Szóstek, Anna Z.; Łukasik, Karolina; Carotenuto, Claudiopietro; Ietta, Francesca; Romagnoli, Roberta; Ferretti, Cristina; Paulesu, Luana; Wołczyński, Sławomir; Skarżyński, Dariusz J. Bisphenol A modulates receptivity and secretory function of human decidual cells: an in vitro study. Reproduction 2015, 150(2): 115-125 (doi: 10.1530/REP-14-0601).
  4. Sztachelska, Maria; Czerniecki, Jan. Jakość nasienia. Czy to kwestia tylko męskiego zdrowia?. ARTNewsletter 2015, 9(2): 25-26 (pdf).

2014

  1. Brünnert, Daniela; Sztachelska, Maria; Bornkessel, Frauke; Treder, Nora; Wołczyński, Sławomir; Goyal, Pankaj; Zygmunt, Marek. Lysophosphatidic acid and sphingosine 1-phosphate metabolic pathways and their receptors are differentially regulated during decidualization of human endometrial stromal cells. Molecular Human Reproduction 2014, 20(10): 1016-1025 (doi: 10.1093/molehr/gau051).
  2. Malinowski, Paweł; Milewski, Robert; Ziniewicz, Piotr; Milewska, Anna J.; Czerniecki, Jan; Wołczyński, Sławomir. The use of data mining methods to predict the result of infertility treatment using the IVF ET method. Studies in Logic, Grammar and Rhetoric 2014, 39(52): 67-74 (doi: 10.2478/slgr-2014-0044).
  3. Rod, Anne; Jarząbek, Katarzyna; Wołczyński, Sławomir; Benhaim, Annie; Reznik, Yves; Denoual-Ziad, Christine; Herlicoviez, Michel; Mittre, Hervé. ESR1 and FSHR gene polymorphisms influence ovarian response to FSH in poor responder women with normal FSH levels. Endocrinology & Metabolic Syndrome 2014, 3(3): art. no 1000141 (1-5) (doi: 10.4172/2161-1017.1000141).
  4. Świątecka, Jolanta; Bielawski, Tomasz; Anchim, Tomasz; Leśniewska, Monika; Milewski, Robert; Wołczyński, Sławomir. Oocyte zona pellucida and meiotic spindle birefringence as a biomarker of pregnancy rate outcome in IVF-ICSI treatment [Dwójłomność osłonki przejrzystej i wrzeciona kariokinetycznego oocytu jako czynnik predykcji wskaźnika ciąż w leczeniu IVF-ET]. Ginekologia Polska 2014, 85(4): 264-271 (doi: 10.17772/gp/1722).

2013

  1. Delvaux, David; Kerff, Frederic; Murty, Mamidanna R. V. S.; Lakaye, Bernard; Czerniecki, Jan; Kohn, Gregory; Wins, Pierre; Herman, Raphael; Gabelica, Valerie; Heuze, Fabien; Tordoir, Xavier; Maree, Raphael; Matagne, Andre; Charlier, Paulette; De Pauw, Edwin; Bettendorff, Lucien. Structural determinants of specificity and catalytic mechanism in mammalian 25-kDa thiamine triphosphatase. Biochimica et Biophysica Acta-General Subjects 2013, 1830(10): 4513-4523 (doi: 10.1016/j.bbagen.2013.05.014).
  2. Jarząbek, Katarzyna; Koda, Mariusz; Walentowicz-Sadlecka, Małgorzata; Grabiec, Marek; Laudański, Piotr; Wołczyński, Sławomir. Altered expression of ERs, aromatase, and COX2 connected to estrogen action in type 1 endometrial cancer biology. Tumor Biology 2013, 34(6): 4007-4016 (doi: 10.1007/s13277-013-0991-9).
  3. Malinowski, Paweł; Milewski, Robert; Ziniewicz, Piotr; Milewska, Anna J.; Czerniecki, Jan; Wołczyński, Sławomir. Classification issue in the IVF ICSI/ET data analysis: early treatment outcomes prognosis. Studies in Logic, Grammar and Rhetoric 2013, 35(48): 103-115 (doi: 10.2478/slgr-2013-0034).
  4. Milewski, Robert; Milewska, Anna J.; Czerniecki, Jan; Leśniewska, Monika; Wołczyński, Sławomir. Analiza profilu demograficznego pacjentów leczonych z powodu niepłodności metodami rozrodu wspomaganego w latach 2005-2010 [Analysis of the demographic profile of patients treated for infertility using assisted reproductive techniques in 2005-2010]. Ginekologia Polska 2013, 84(7): 609-614 (doi: 10.17772/gp/1612).
  5. Patricelli, Dario; Sielezniew, Marcin; Ponikwicka-Tyszko, Donata; Ratkiewicz, Mirosław; Bonelli, Simona; Barbero, Francesca; Witek, Magdalena; Buś, Magdalena M.; Rutkowski, Robert; Balletto, Emilio. Contrasting genetic structure of rear edge and continuous range populations of a parasitic butterfly infected by Wolbachia. BMC Evolutionary Biology 2013, 13: art. no 14 (1-13) (doi: 10.1186/1471-2148-13-14).

2012

  1. Jarząbek, Katarzyna; Kozłowski, Leszek; Milewski, Robert; Wołczyński, Sławomir. KiSS1/GPR54 and estrogen-related gene expression profiles in primary breast cancer. Oncology Letters 2012, 3(4): 930-934 (doi: 10.3892/ol.2012.582).
  2. Jarząbek, Katarzyna; Wołczyński, Sławomir; Leśniewicz, Ryszard; Plessis, G.; Kottler, Marie-Laure. Evidence that FGFR1 loss-of-function mutations may cause variable skeletal malformations in patients with Kallmann syndrome. Advances in Medical Sciences 2012, 57(2): 314-321 (doi: 10.2478/v10039-012-0036-4).
  3. Milewski, Robert; Malinowski, Paweł; Milewska, Anna J.; Ziniewicz, Piotr; Czerniecki, Jan; Pierzyński, Piotr; Wołczyński, Sławomir. Classification issue in the IVF ICSI/ET data analysis. Studies in Logic, Grammar and Rhetoric 2012, 29(42): 75-86.
  4. Ponikwicka-Tyszko, Donata; Kotula-Balak, Małgorzata; Jarząbek, Katarzyna; Bilińska, Barbara; Wołczyński, Sławomir. The DAX1 mutation in a patient with hypogonadotropic hypogonadism and adrenal hypoplasia congenita causes functional disruption of induction of spermatogenesis. Journal of Assisted Reproduction and Genetics 2012, 29(8): 811-816 (doi: 10.1007/s10815-012-9778-y).
  5. Sielezniew, Marcin; Rutkowski, Robert; Ponikwicka-Tyszko, Donata; Ratkiewicz, Mirosław; Dziekańska, Izabela; Švitra, Giedrius. Differences in genetic variability between two ecotypes of the endangered myrmecophilous butterfly Phengaris (=Maculinea) alcon – the setting of conservation priorities. Insect Conservation and Diversity 2012, 5(3): 223-236 (doi: 10.1111/j.1752-4598.2011.00163.x).

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Foreign co-operation B&PoHR

Collaborations

  • Prof. Nafis Rahman Department of Physiology, Institute of Biomedicine, Faculty of Medicine, University of Turku, Finland
  • Xiangdong Li State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University, Beijing, China
  • Prof. Marek Zygmunt Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe, Universitätsmedizin Greifswald, Germany
  • Prof. dr hab. Violetta Dymicka-Piekarska, Department of Clinical Laboratory Diagnostics, Faculty of Pharmacy with the Division of Laboratory Medicine Medical University of Białystok, Poland
  • Dr hab. Wioletta Ratajczak-Wrona, Departament of Immunology, Faculty of Pharmacy with the Division of Laboratory Medicine Medical University of Białystok, Poland

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Current projects B&PoHR

Research projects:

  1. Establishment and characterisation of immortalised PCOS and control adipocyte cell lines – Statutory work for the year 2024.
  2. Studies on the mechanism of human cytomegalovirus persistence in reproductive tract cancer cells – Statutory work for the year 2023.
  3. Development of a research model of uterine dysfunction during the ovarian cycle and early pregnancy – Functional role of steroid hormone receptors in the development of receptive endometrium – Statutory work for the year 2022.
  4. Functional characterisation of ovarian-specific genes potentially involved in the pathophysiology of endometriosis (Polish Gynaecological Society Grant).
  5. The role of lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P) and their receptors in the proliferation, migration and decidualization of human endometrial stromal cells (NCN Preludium, project nr: 2014/13/N/NZ4/04408).
  6. Molecular mechanisms of interaction between progesterone, mifepristone and nuclear and membrane progesterone receptors in gonadal cancer cells in vitro (NCN Preludium, project nr: 2013/09/N/NZ5/01831).
  7. The impact of antropogenic xenoestrogens in male infertility development (NCN Opus, project nr: 2012/05/B/NZ7/02391).

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Publications I&FM

2024

  1. Juśkiewicz, Jerzy; Fotschki, Bartosz; Stępniowska, Anna; Cholewińska, Ewelina; Napiórkowska, Dorota; Marzec, Aleksandra; Brzuzan, Łucja; Fotschki, Joanna; Żary-Sikorska, Ewa; Ognik, Katarzyna. Dietary fiber with functional properties counteracts the thwarting effects of copper nanoparticles on the microbial enzymatic activity and short-chain fatty acid production in the feces of rats. Polish Journal of Food and Nutrition Sciences 2024, 74(4): 363-375 (10.31883/pjfns/194694).

  2. Kuśmierek, Paulina; Mikołajczyk, Mateusz; Złotkowska, Dagmara; Łowczak, Anna; Mikołajczyk, Anita. Low back pain prevention behaviors and beliefs among the Polish population in a cross-sectional survey. Frontiers in Public Health 2024, 12: art. no 1396558 (1-11) (10.3389/fpubh.2024.1396558).

  3. Mikołajczyk, Mateusz; Złotkowska, Dagmara; Mikołajczyk, Anita. Impact on human health of Salmonella spp. and their lipopolysaccharides: possible therapeutic role and asymptomatic presence consequences. International Journal of Molecular Sciences 2024, 25(22): art. no 11868 (1-15) (10.3390/ijms252211868).

  4. Ogrodowczyk, Anna M.; Romaszko, Ewa. Study protocol: The role of milk matrix lipids in programming the immunoreactivity of proteins derived from lactic acid bacteria. PLoS ONE 2024, 19(5): art. no e0301477 (1-17) (10.1371/journal.pone.0301477).

  5. Złotkowska, Dagmara; Markiewicz, Lidia H.; Ogrodowczyk, Anna M.; Wróblewska, Barbara; Wasilewska, Ewa. Enhanced effect of β-lactoglobulin immunization in mice with mild intestinal deterioration caused by low-dose dextran sulphate sodium: a new experimental approach to allergy studies. Nutrients 2024, 16(20): art. no 3430 (1-21) (10.3390/nu16203430).

  6. Zuurveld, Marit;. Ogrodowczyk, Anna M.; Benedé, Sara; Czolk, Rebecca; Bavaro, Simona L.; Randow, Stefanie; Markiewicz, Lidia H.; Wróblewska, Barbara; Molina, Elena; Kuehn, Annette; Holzhauser, Thomas; Willemsen, Linette E. M. Allergenic shrimp tropomyosin distinguishes from a non-allergenic chicken homolog by pronounced intestinal barrier disruption and downstream Th2 responses in epithelial and dendritic cell (co)culture. Nutrients 2024, 16(8): art. no 1192 (1-15) (10.3390/nu16081192).

2023

  1. Fotschki, Bartosz; Cholewińska, Ewelina; Ognik, Katarzyna; Sójka, Michał; Milala, Joanna; Fotschki, Joanna; Wiczkowski, Wiesław; Juśkiewicz, Jerzy. Dose-related regulatory effect of raspberry polyphenolic extract on cecal microbiota activity, lipid metabolism and inflammation in rats fed a diet rich in saturated fats. Nutrients 2023, 15(2): art. no 354 (1-16) (10.3390/nu15020354).
  2. Fotschki, Bartosz; Ognik, Katarzyna; Fotschki, Joanna; Napiórkowska, Dorota; Cholewińska, Ewelina; Krauze, Magdalena; Juśkiewicz, Jerzy. Chromium nanoparticles together with a switch away from high-fat/low-fiber dietary habits enhances the pro-healthy regulation of liver lipid metabolism and inflammation in obese rats. International Journal of Molecular Sciences 2023, 24(3): art. no 2940 (1-15) (10.3390/ijms24032940).
  3. Fotschki, Joanna; Ogrodowczyk, Anna M.; Wróblewska, Barbara; Juśkiewicz, Jerzy. Side streams of vegetable processing and Its bioactive compounds support microbiota, intestine milieu, and immune system. Molecules 2023, 28(11): art. no 4340 (1-27) (10.3390/molecules28114340).
  4. Hryhorenko, Nataliia; Krupa-Kozak, Urszula; Bączek, Natalia; Rudnicka, Bogumiła; Wróblewska, Barbara. Gluten-free bread enriched with whole-grain red sorghum flour gains favourable technological and functional properties and consumers acceptance. Journal of Cereal Science 2023, 110: art. no 103646 (1-8) (10.1016/j.jcs.2023.103646).
  5. Nalepa, Beata; Markiewicz, Lidia H. Microbiological biodiversity of regional cow, goat and ewe milk cheeses produced in Poland and antibiotic resistance of lactic acid bacteria isolated from them. Animals 2023, 13(1): art. no 168 (1-16) (10.3390/ani13010168).
  6. Ogrodowczyk, Anna M.; Modzelewska-Kapituła, Monika. Recent Advances in Fermented Milk and Meat Products – Quality, Nutritional Value and Safety. Animals 2023, 13(13): art. no 2048 (1-5) (10.3390/ani13132048).
  7. Wróblewska, Barabara; Ogrodowczyk, Anna; Wasilewska, Ewa. Immunoreactive proteins of Capsicum-based spices as a threat to human health: mass spectrometry analysis and in silico mapping. Scientific Reports 2023, 13(1): art. no 17723 (1-16) (10.1038/s41598-023-44775-3).
  8. Wróblewska, Barbara. Food Allergens. In: Chemical and Functional Properties of Food Components: Fourth Edition 2023, 339-361 (10.1201/9781003265955-12).
  9. Wróblewska, Barbara; Kuliga, Aleksandra; Wnorowska, Kinga. Bioactive Dairy-Fermented Products and Phenolic Compounds: Together or Apart. Molecules 2023, 28(24): art. no 8081 (1-35) (10.3390/molecules28248081).
  10. Złotkowska, Dagmara; Kuczyński, Mateusz; Fuc, Ewa; Fotschki, Joanna; Wróblewska, Barbara. Glycation of Whey Proteins Increases the Ex Vivo Immune Response of Lymphocytes Sensitized to β-Lactoglobulin. Nutrients 2023, 15(14): art. no 3110 (1-15) (10.3390/nu15143110).

2022

  1. Cernava, Tomislav; Rybakova, Daria; Buscot, François; Clavel, Thomas; McHardy, Alice C.; Meyer, Fernando; Meyer, Folker; Overmann, Jörg; Stecher, Bärbel; Sessitsch, Angela; Schloter, Michael; Berg, Gabriele; Arruda, Paulo; Bartzanas, Thomas; Kostic, Tanja; Brennan, Paula I.; Biazotti, Bárbara B.; Champomier-Verges, Marie-Christine; Charles, Trevor; Coakley, Mairead; Cotter, Paul; Cowan, Don; D’Hondt, Kathleen; Ferrocino, Ilario; Foterek, Kristina; Herrero-Corral, Gema; Huitema, Carly; Jansson, Janet; Liu, Shuang-Jiang; Malloy, Paula; Maguin, Emmanuelle; Markiewicz, Lidia H.; Mcclure, Ryan; Moser, Andreas; Roovers, Jolien; Ryan, Matthew; Sarand, Inga; Schelkle, Bettina; Meisner, Annelein; Schurr, Ulrich; Selvin, Joseph; Tsakalidou, Effie; Wagner, Martin; Wakelin, Steve; Wiczkowski, Wiesław; Winkler, Hanna; Xiao, Juanjuan; Bunthof, Christine J.; de Souza, Rafael Soares Correa; Sanz, Yolanda; Lange, Lene; Smidt, Hauke. Metadata harmonization – Standards are the key for a better usage of omics data for integrative microbiome analysis. Environmental Microbiome 2022, 17: art. no 33 (1-10) (10.1186/s40793-022-00425-1).
  2. Kocot, Aleksandra M. Special Issue: coatings and thin films as functional and protective structures in food technology and their potential in packaging applications. Coatings 2022, 12(8): art. no 1170 (1-3) (10.3390/coatings12081170).
  3. Kocot, Aleksandra M.; Jarocka-Cyrta, Elżbieta; Drabińska, Natalia. Overview of the importance of biotics in gut barrier integrity. International Journal of Molecular Sciences 2022, 23(5): art. no 2896 (1-32) (10.3390/ijms23052896).
  4. Kocot, Aleksandra M.; Wróblewska, Barbara. Nutritional strategies for autophagy activation and health consequences of autophagy impairment. Nutrition 2022, 103-104: art. no 111686 (1-10) (10.1016/j.nut.2022.111686).
  5. Kocot, Aleksandra M.; Wróblewska, Barbara. Zaburzona autofagia jako czynnik etiologiczny zróżnicowanych jednostek chorobowych [Impaired autophagy as an etiological factor of various disease entities]. Lekarz Wojskowy / Military Phisician 2022, 100(1): 12-18 (10.53301/lw/143317).
  6. Markiewicz, Lidia H.; Ogrodowczyk, Anna M.; Wiczkowski, Wiesław; Wróblewska, Barbara. Phytate hydrolysate differently modulates the immune response of human healthy and cancer colonocytes to intestinal bacteria. Nutrients 2022, 14(20): art. no 4234 (1-18) (10.3390/nu14204234).
  7. Meisner, Annelein; Wepner, Beatrix; Kostic, Tanja; van Overbeek, Leo S.; Bunthof, Christine J.; de Souza, Rafael Soares Correa; Olivares, Marta; Sanz, Yolanda; Lange, Lene; Fischer, Doreen; Sessitsch, Angela; Smidt, Hauke; Arruda, Paulo; Bartzanas, Thomas; Berg, Gabriele; Brennan, Paula I.; Bort Biazotti, Bárbara; Champomier-Verges, Marie-Christine; Charles, Trevor; Coakley, Mairead; Cotter, Paul; Cowan, Don; D’Hondt, Kathleen; Ferrocino, Ilario; Foterek, Kristina; Herrero-Corral, Gema; Huitema, Carly; Jansson, Janet; Liu, Shuang-Jiang; Malloy, Paula; Maguin, Emmanuelle; Markiewicz, Lidia H.; Mcclure, Ryan; Moser, Andreas; Roovers, Jolien; Ryan, Matthew; Sarand, Inga; Schelkle, Bettina; Schloter, Michael; Schurr, Ulrich; Selvin, Joseph; Tsakalidou, Effie; Wagner, Martin; Wakelin, Steve; Wiczkowski, Wiesław; Winkler, Hanna; Xiao, Juanjuan. Calling for a systems approach in microbiome research and innovation. Current Opinion in Biotechnology 2022, 73: 171-178 (10.1016/j.copbio.2021.08.003).
  8. Ogrodowczyk, Anna M.; Jeż, Maja; Wróblewska, Barbara. The manifold bioactivity and immunoreactivity of microbial proteins of cow and human mature milk in late lactation. Animals 2022, 12(19): art. no 2605 (1-24) (10.3390/ani12192605).
  9. Stępniowska, Anna; Juśkiewicz, Jerzy; Tutaj, Krzysztof; Fotschki, Joanna; Fotschki, Bartosz; Ognik, Katarzyna. Effect of chromium picolinate and chromium nanoparticles added to low- or high-fat diets on chromium biodistribution and the blood level of selected minerals in rats. Polish Journal of Food and Nutrition Sciences 2022, 72(3): 229-238 (10.31883/pjfns/151750).
  10. Wróblewska, Barbara; Kubicka, Ewa; Semenowicz, Ewelina; Ogrodowczyk, Anna; Mikołajczyk, Anita; Złotkowska, Dagmara. The immune system Response to 15-kDa barley protein: a mouse model study. Nutrients 2022, 14(20): art. no 4371 (1-13) (10.3390/nu14204371).

2021

  1. Fuc, Ewa; Złotkowska, Dagmara; Wasilewska, Ewa; Wróblewska, Barbara. Ova-experienced cd4+ t cell transfer and chicken protein challenge affect the immune response to ova in a murine model. International Journal of Molecular Sciences 2021, 22(12): art. no 6573 (1-12) (10.3390/ijms22126573).
  2. Kocot, Aleksandra M.; Wróblewska, Barbara. Fermented products and bioactive food compounds as a tool to activate autophagy and promote the maintenance of the intestinal barrier function. Trends in Food Science & Technology 2021, 118(Part B): 905-919 (10.1016/j.tifs.2021.11.014).
  3. Kocot, Aleksandra M.; Wróblewska, Barbara; Lopez Cabo, Marta. Operational culture conditions determinate benzalkonium chloride resistance in L. monocytogenes-E.coli dual species biofilms. International Journal of Food Microbiology 2021, 360: art. no 109441 (1-7) (10.1016/j.ijfoodmicro.2021.109441).
  4. Markiewicz, Lidia H.; Ogrodowczyk, Anna M.; Wiczkowski, Wiesław; Wróblewska, Barbara. Phytate and butyrate differently influence the proliferation, apoptosis and survival pathways in human cancer and healthy colonocytes. Nutrients 2021, 13(6): art. no 1887 (1-16) (10.3390/nu13061887).
  5. Nasiłowska, Justyna; Kocot, Aleksandra; Osuchowska, Paulina N.; Sokołowska, Barbara. High-pressure-induced sublethal injuries of food pathogens – microscopic assessment. Foods 2021, 10(12): art. no 2940 (1-13) (10.3390/foods10122940).
  6. Ogrodowczyk, Anna M.; Dimitrov, Ivan; Wróblewska, Barbara. Two faces of milk proteins peptides with both allergenic and multidimensional health beneficial impact- integrated in vitro/in silico approach. Foods 2021, 10(1): art. no 163 (1-24) (10.3390/foods10010163).
  7. Ogrodowczyk, Anna M.; Drabińska, Natalia. Crossroad of tradition and innovation – the application of lactic acid fermentation to increase the nutritional and health-promoting potential of plant-based food products – a review. Polish Journal of Food and Nutrition Sciences 2021, 71(2): 107-134 (10.31883/pjfns/134282).
  8. Ogrodowczyk, Anna M.; Kalicki, Bolesław; Wróblewska, Barbara. The effect of lactic acid fermentation with different bacterial strains on the chemical composition, immunoreactive properties, and sensory quality of sweet buttermilk. Food Chemistry 2021, 353: art. no 129512 (1-11) (10.1016/j.foodchem.2021.129512).
  9. Złotkowska, Dagmara; Stachurska, Emilia; Fuc, Ewa; Wróblewska, Barbara; Mikołajczyk, Anita; Wasilewska Ewa. Differences in regulatory mechanisms induced by β-Lactoglobulin and κ-Casein in cow’s milk allergy mouse model – in vivo and ex vivo studies. Nutrients 2021, 13(2): art. no 349 (1-16) (10.3390/nu13020349).

2020

  1. Chudzik-Kozłowska, Justyna P.; Wasilewska, Ewa; Złotkowska, Dagmara. Evaluation of immunoreactivity of pea (Pisum sativum) albumins in BALB/c and C57BL/6 mice. Journal of Agricultural and Food Chemistry 2020, 68(13): 3891-3902 (10.1021/acs.jafc.0c00297).
  2. Fotschki, Joanna; Wróblewska, Barbara; Fotschki, Bartosz; Kalicki, B.; Rigby, N.; Mackie, A. Microbial transglutaminase alters the immunogenic potential and cross reactivity of horse and cow milk proteins. Journal of Dairy Science 2020, 103(3): 2153-2166 (10.3168/jds.2019-17264).
  3. Ogrodowczyk, Anna M.; Zakrzewska, Magdalena; Romaszko, Ewa; Wróblewska, Barbara. Gestational dysfunction-driven diets and probiotic supplementation correlate with the profile of allergen-specific antibodies in the serum of allergy sufferers. Nutrients 2020, 12(8): art. no 2381 (1-25) (10.3390/nu12082381).
  4. Wróblewska, Barbara; Kaliszewska-Suchodoła, Anna; Fuc, Ewa; Markiewicz, Lidia H.; Ogrodowczyk, Anna M.; Złotkowska, Dagmara; Wasilewska, Ewa. Effect of low-immunogenic yogurt drinks and probiotic bacteria on immunoreactivity of cow’s milk proteins and tolerance induction – in vitro and in vivo studies. Nutrients 2020, 12(11): art. no 3390 (1-23) (10.3390/nu12113390).

2019

  1. Będzichowska, Agata; Przekora, Jędrzej; Stapińska-Syniec, Angelika; Guzek, Aneta; Murawski, Piotr; Jobs, Katarzyna; Wróblewska, Barbara; Kalicki, Bolesław. Frequency of infections caused by ESBL-producing bacteria in a pediatric ward – single-center five-year observation. Archives of Medical Science 2019, 15(3): 688-693 (10.5114/aoms.2017.72407).
  2. Drabińska, Natalia; Jarocka-Cyrta, Elżbieta; Złotkowska, Dagmara; Abramowicz, Paweł; Krupa-Kozak, Urszula. Daily oligofructose-enriched inulin intake impacts bone turnover markers but not the cytokine profile in pediatric patients with celiac disease on a gluten-free diet: Results of a randomised, placebo-controlled pilot study. Bone 2019, 122: 184-192 (10.1016/j.bone.2019.03.001).
  3. Fotschki, Bartosz; Jurgoński, Adam; Fotschki, Joanna; Majewski, Michał; Ognik, Katarzyna; Juśkiewicz, Jerzy. Dietary chicory inulin-rich meal exerts greater healing effects than fructooligosaccharide preparation in rats with trinitrobenzenesulfonic acid-induced necrotic colitis. Polish Journal of Food and Nutrition Sciences 2019, 69(2): 147-155 (10.31883/pjfns-2019-0013).
  4. Fuc, Ewa; Złotkowska, Dagmara; Wróblewska, Barbara. Milk and meat allergens from bos taurus β-lactoglobulin, α-casein, and bovine serum albumin: an in-vivo study of the immune response in mice. Nutrients 2019, 11(9): art. no 2095 (1-14) (10.3390/nu11092095).
  5. Lozano-Ojalvo, Daniel; Benedé, Sara; Antunes, Celia M.; Bavaro, Simona L.; Bouchaud, Grégory; Costa, Ana; Denery-Papini, Sandra; Díaz-Perales, Araceli; Garrido-Arandia, María; Gavrovic-Jankulovic, Marija; Hayen, Simone; Martínez-Blanco, Mónica; Molina, Elena; Monaci, Linda; Pieters, Raymond H. H.; Villemin, Clelia; Wichers, Harry J.; Wróblewska, Barbara; Willemsen, Linette E. M.; Roggen, Erwin L.; van Bilsen, Jolanda H. M. Applying the Adverse Outcome Pathway (AOP) for food sensitization to support in vitro testing strategies. Trends in Food Science & Technology 2019, 85: 307-319 (10.1016/j.tifs.2019.01.014).
  6. Mikołajczyk, Anita; Złotkowska, Dagmara. Subclinical lipopolysaccharide from Salmonella enteritidis induces dysregulation of bioactive substances from selected brain sections and glands of neuroendocrine axes. Toxins 2019, 11(2): art. no 91 (1-24) (10.3390/toxins11020091 ).
  7. Mikołajczyk, Anita; Złotkowska, Dagmara. Subclinical lipopolysaccharide from Salmonella enteritidis induces neuropeptide dysregulation in the spinal cord and the dorsal root ganglia. BMC Neuroscience 2019, 20(1): art. no 18 (1-12) (10.1186/s12868-019-0502-z).
  8. Nalepa, Beata; Olszewska, Magdalena A.; Markiewicz, Lidia H.; Aljewicz, Marek. Composition and significance of bacterial microbiota and volatile organic compounds of swiss-dutch-type cheese as determined by PCR-DGGE and HS-GC. Polish Journal of Food and Nutrition Sciences 2019, 69(3): 267-278 (10.31883/pjfns/109899).
  9. Wasilewska, Ewa; Złotkowska, Dagmara; Wróblewska, Barbara. Yogurt starter cultures of Streptococcus thermophilus and Lactobacillus bulgaricus ameliorate symptoms and modulate the immune response in mouse model of dextran sulfate sodium-induced colitis. Journal of Dairy Science 2019, 102(1): 37-53 (10.3168/jds.2018-14520).
  10. Wróblewska, Barbara; Kaliszewska-Suchodoła, Anna; Markiewicz, Lidia H.; Szyc, Anna M.; Wasilewska, Ewa. Whey prefermented with beneficial microbes modulates immune response and lowers responsiveness to milk allergens in mouse model. Journal of Functional Foods 2019, 54: 41-52 (10.1016/j.jff.2018.12.032).
  11. Żary-Sikorska, Ewa; Fotschki, Bartosz; Fotschki, Joanna; Wiczkowski, Wiesław; Juśkiewicz, Jerzy. Preparations from purple carrots containing anthocyanins improved intestine microbial activity, serum lipid profile and antioxidant status in rats. Journal of Functional Foods 2019, 60: art. no 103442 (1-8) (10.1016/j.jff.2019.103442).

2018

  1. Drabińska, Natalia; Jarocka-Cyrta, Elżbieta; Markiewicz, Lidia H.; Krupa-Kozak, Urszula. The effect of oligofructose-enriched inulin on faecal bacterial counts and microbiota-associated characteristics in celiac disease children following a gluten-free diet: results of a randomized, placebo-controlled trial. Nutrients 2018, 10(2): art. no 201 (1-11) (doi: 10.3390/nu10020201).
  2. Fuc, Ewa; Złotkowska, Dagmara; Stachurska, Emilia; Wróblewska, Barbara. Immunoreactive properties of α-casein and κ-casein: ex vivo and in vivo studies. Journal of Dairy Science 2018, 101(12): 10703-10713 (doi: 10.3168/jds.2018-14915).
  3. Mikołajczyk, Anita; Złotkowska, Dagmara. Neuroimmunological implications of subclinical lipopolysaccharide from Salmonella enteritidis. International Journal of Molecular Sciences 2018, 19(10): art. no 3274 (1-20) (doi: 10.3390/ijms19103274).
  4. Nalepa, Beata; Olszewska, Magdalena A.; Markiewicz, Lidia H. Seasonal variances in bacterial microbiota and volatile organic compounds in raw milk. International Journal of Food Microbiology 2018, 267: 70-76 (doi: 10.1016/j.ijfoodmicro.2017.12.024).
  5. Wasilewska, Ewa; Wróblewska, Barbara. Effectiveness and safety of probiotic preparations in clinical treatment of inflammatory bowel disease [Efektywność i bezpieczeństwo preparatów probiotycznych stosowanych w terapii nieswoistych zapaleń jelit]. Postępy Higieny i Medycyny Doświadczalnej 2018, 72: 159-174 (doi: 10.5604/01.3001.0011.6471).
  6. Wróblewska, Barbara; Juśkiewicz, Jerzy; Kroplewski, Bartosz; Jurgoński, Adam; Wasilewska, Ewa; Złotkowska, Dagmara; Markiewicz, Lidia H. The effects of whey and soy proteins on growth performance, gastrointestinal digestion, and selected physiological responses in rats. Food & Function 2018, 9(3): 1500-1509 (doi: 10.1039/C7FO01204G).
  7. Wróblewska, Barbara; Szyc, Anna M.; Markiewicz, Lidia H.; Zakrzewska, Magdalena; Romaszko, Ewa. Increased prevalence of eating disorders as a biopsychosocial implication of food allergy. Plos One 2018, 13(6): art. no e0198607 (1-19) (doi: 10.1371/journal.pone.0198607).

2017

  1. Jurgoński, Adam; Juśkiewicz, Jerzy; Fotschki, Bartosz; Kołodziejczyk, Krzysztof; Milala, Joanna; Kosmala, Monika; Grzelak-Głaszczyk, Katarzyna; Markiewicz, Lidia H. Metabolism of strawberry mono- and dimeric ellagitannins in rats fed a diet containing fructo-oligosaccharides. European Journal of Nutrition 2017, 56(2): 853-864 (doi: 10.1007/s00394-015-1133-5).
  2. Kacik, Joanna; Wróblewska, Barbara; Lewicki, Sławomir; Zdanowski, Robert; Kalicki, Bolesław. Serum diamine oxidase in pseudoallergy in the pediatric population. In: Current Concepts in Medical Research and Practice. Ed. Pokorski, M. Advances in Experimental Medicine and Biology, vol. 1039. Springer, Cham 2017 (ISBN 978-3-319-74149-9 / 0065-2598), 35-44 (doi: 10.1007/5584_2017_81).
  3. Krupa-Kozak, Urszula; Markiewicz, Lidia H.; Lamparski, Grzegorz; Juśkiewicz, Jerzy. Administration of inulin-supplemented gluten-free diet modified calcium absorption and caecal microbiota in rats in a calcium-dependent manner. Nutrients 2017, 9(7): art. no 702 (1-19) (doi: 10.3390/nu9070702).
  4. Mikołajczyk, Anita; Gonkowski, Sławomir; Złotkowska, Dagmara. Modulation of the main porcine enteric neuropeptides by a single low-dose of lipopolysaccharide (LPS) Salmonella Enteritidis. Gut Pathogens 2017, 9: art. no 73 (1-10) (doi: 10.1186/s13099-017-0225-6).
  5. Nalepa, Beata; Markiewicz, Lidia H. PCR-DGGE markers for qualitative profiling of microbiota in raw milk and ripened cheeses. LWT-Food Science and Technology 2017, 84: 168-174 (doi: 10.1016/j.lwt.2017.05.057).
  6. Świątecka, Dominika; Złotkowska, Dagmara; Markiewicz, Lidia H.; Szyc, Anna M.; Wróblewska, Barbara. Impact of whey proteins on the systemic and local intestinal level of mice with diet induced obesity. Food & Function 2017, 8(4): 1708-1717 (doi: 10.1039/C6FO01311B).
  7. van Bilsen, Jolanda H. M.; Sienkiewicz-Szłapka, Edyta; Lozano-Ojalvo, Daniel; Willemsen, Linette E.; Antunes, Celia M.; Molina, Elena; Smit, Joost J.; Wróblewska, Barbara; Wichers, Harry J.; Knol, Edward F.; Ladics, Gregory S.; Pieters, Raymond H. H.; Denery-Papini, Sandra; Vissers, Yvonne M.; Bavaro, Simona L.; Larré, Colette; Verhoeckx, Kitty C.; Roggen, Erwin L. Application of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteins. Clinical and Translational Allergy 2017, 7: art. no 13 (1-18) (doi: 10.1186/s13601-017-0152-0).
  8. Wróblewska, Barbara. Alergeny w żywności. In: Chemia żywności. Tom 2. Biologiczne właściwości składników żywności. Ed. Sikorski, Zdzisław E.; Staroszczyk, Hanna. Polskie Wydawnictwo Naukowe, Warszawa 2017 (ISBN 978-83-01-19626-4), Rozdział 4: 115-142.

2016

  1. Fiedorowicz, Ewa; Markiewicz, Lidia H.; Sidor, Katarzyna; Świątecka, Dominika; Cieślińska, Anna; Matysiewicz, Michał; Piskorz-Ogórek, Krystyna; Sienkiewicz-Szłapka, Edyta; Teodorowicz, Małgorzata; Świątecki, Aleksander; Kostyra, Elżbieta. The influence of breast milk and infant formulae hydrolysates on bacterial adhesion and Caco-2 cells functioning. Food Research International 2016, 89(Part 1): 679-688 (doi: 10.1016/j.foodres.2016.09.022).
  2. Fotschki, Joanna; Szyc, Anna M.; Lapara, J. Moises; Markiewicz, Lidia H.; Wróblewska, Barbara. Immune-modulating properties of horse milk administered to mice sensitized to cow milk. Journal of Dairy Science 2016, 99(12): 9395-9404 (doi: 10.3168/jds.2016-11499).
  3. Fotschki, Joanna; Szyc, Anna M.; Wróblewska, Barbara. Wpływ efektywności procesów trawiennych na potencjał immunogenny alergenów. In: Medycyna XXI wieku – wybrane zagadnienia. Ed.: Skopińska-Różewska, Ewa; Siwicki, Andrzej K.; Zdanowski, Robert. Studio Wydawnicze Edycja, Olsztyn 2016 (ISBN 978-83-941917-7-1), 189-200.
  4. Jeż, Maja; Markiewicz, Lidia H.; Wróblewska, Barbara; Szyc, Anna M. Mikrobiota przewodu pokarmowego człowieka w aspekcie aktywności fitazy. In: Badania i Rozwój Młodych Naukowców w Polsce. Ed. Leśny, Jacek; Panfil, Monika; Nyćkowiak, Jędrzej. Wydawnictwo Młodzi Naukowcy 2016 (ISBN 978-83-65362-13-1), 40-47.
  5. Jóźwik, Artur; Strzałkowska, Nina; Lipińska, Paulina; Markiewicz-Kęszycka, Maria; Łysek-Gładysińska, Małgorzata; Wróblewska, Barbara; Stanisławska, Iwona. The effect of breed and the feeding system on the activity of glycosidases in cow’s milk. Animal Science Papers and Reports 2016, 34(1): 41-52 (pdf).
  6. Jóźwik, Artur; Strzałkowska, Nina; Markiewicz-Kęszycka, Maria; Krzyżewski, Józef; Lipińska, Paulina; Rutkowska, Jarosława; Wróblewska, Barbara; Klusek, Joanna; Cooper, Ross G. Effects of replacing rapeseed cake with linseed cake in a corn-grass silage-based diet for milking cows. Animal Science Papers and Reports 2016, 34(2): 129-142 (pdf).
  7. Kaliszewska, Anna; Martinez, V.; Laparra, Jose M. Proinflammatory responses driven by non-gluten factors are masked when they appear associated to gliadins. Food and Chemical Toxicology 2016, 95: 89-95 (doi: 10.1016/j.fct.2016.06.030).
  8. Kostyra, Henryk; Kostyra, Elżbieta; Złotkowska, Dagmara. Chemia bionieorganiczna i bioorganiczna żywności. Część 1 [Bioinorganic and bioorganic chemistry of food. Part 1]. Żywność. Nauka. Technologia. Jakość 2016, 1(104): 180-182 (pdf).
  9. Kostyra, Henryk; Kostyra, Elżbieta; Złotkowska, Dagmara. Chemia bionieorganiczna i bioorganiczna żywności. Część 2 [Bioinorganic and bioorganic chemistry of food. Part 2]. Żywność. Nauka. Technologia. Jakość 2016, 2(105): 145-148 (pdf).
  10. Kostyra, Henryk; Kostyra, Elżbieta; Złotkowska, Dagmara. Chemia bionieorganiczna i bioorganiczna żywności. Część 3 [Bioinorganic and bioorganic chemistry of food. Part 3]. Żywność. Nauka. Technologia. Jakość 2016, 3(106): 153-155 (pdf).
  11. Krupa-Kozak, Urszula; Świątecka, Dominika; Bączek, Natalia; Brzóska, Małgorzata M. Inulin and fructooligosaccharide affect: In vitro calcium uptake and absorption from calcium-enriched gluten-free bread. Food & Function 2016, 7(4): 1950-1958 (doi: 10.1039/c6fo00140h).
  12. Markiewicz, Lidia H.; Szyc, Anna M.; Wróblewska, Barbara. Kwas fitynowy i produkty jego degradacji w aspekcie diety i działania przeciwnowotworowego. In: Medycyna XXI wieku – wybrane zagadnienia. Ed.: Skopińska-Różewska, Ewa; Siwicki, Andrzej K.; Zdanowski, Robert. Studio Wydawnicze Edycja, Olsztyn 2016 (ISBN 978-83-941917-7-1), 51-61.
  13. Markiewicz, Lidia H.; Szymkiewicz, Agata; Szyc, Anna M.; Wróblewska, Barbara. A simultaneous two-colour detection method of human IgG- and IgE-reactive proteins from lactic acid bacteria. Journal of Microbiological Methods 2016, 126: 72-75 (doi: 10.1016/j.mimet.2016.05.007).
  14. Szyc, Anna M.; Fotschki, Joanna; Markiewicz, Lidia H.; Wróblewska, Barbara. Rola białek bakterii jelitowych w kontekście alergii. In: Medycyna XXI wieku – wybrane zagadnienia. Ed.: Skopińska-Różewska, Ewa; Siwicki, Andrzej K.; Zdanowski, Robert. Studio Wydawnicze Edycja, Olsztyn 2016 (ISBN 978-83-941917-7-1), 201-219.
  15. Świątecka, Dominika; Markiewicz, Lidia H.; Wróblewska, Barbara. The effect of hydrolysates of proteins from rice milk on the physiological response of enterocytes and on the adhesion of bacteria from healthy and allergic people – an in vitro study. Central European Journal of Immunology 2016, 41(4): 363-375 (doi: 10.5114/ceji.2016.65135).
  16. Wasilewska, Ewa; Wróblewska, Barbara. Mikrobiota a metabolizm gospodarza i rozwój otyłości. In: Medycyna XXI wieku – wybrane zagadnienia. Ed.: Skopińska-Różewska, Ewa; Siwicki, Andrzej K.; Zdanowski, Robert. Studio Wydawnicze Edycja, Olsztyn 2016 (ISBN 978-83-941917-7-1), 221-229.
  17. Wróblewska, Barbara; Markiewicz, Lidia H.; Szyc, Anna M.; Dietrich, Mariola A.; Szymkiewicz, Agata; Fotschki, Joanna. Lactobacillus casei LcY decreases milk protein immunoreactivity of fermented buttermilk but also contains IgE-reactive proteins. Food Research International 2016, 83: 95-101 (doi: 10.1016/j.foodres.2016.02.016).
  18. Ziętak, Marika; Kovatcheva-Datchary, Petia; Markiewicz, Lidia H.; Ståhlman, Marcus; Kozak, Leslie P.; Bäckhed, Frederik. Altered microbiota contributes to reduced diet-induced obesity upon cold exposure. Cell Metabolism 2016, 23(6): 1216-1223 (doi: 10.1016/j.cmet.2016.05.001).

2015

  1. Fotschki, Joanna; Szyc, Anna M.; Lapara, J. Moises; Wróblewska, Barbara. Mare’s and cow’s milk: promote similar metabolic effects and expression of innate markers in Caco-2 cells?. Food Research International 2015, 72: 184-190 (doi: 10.1016/j.foodres.2015.04.001).
  2. Fotschki, Joanna; Szyc, Anna M.; Wróblewska, Barbara. Immunoreactivity of lactic acid-treated mare’s milk after simulated digestion. Journal of Dairy Research 2015, 82(1): 78-85 (doi: 10.1017/S0022029914000612).
  3. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 25 [Interactions among food components. Part 25]. Żywność. Nauka. Technologia. Jakość 2015, 1(98): 232-234 (pdf).
  4. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 26 [Interactions among food components. Part 26]. Żywność. Nauka. Technologia. Jakość 2015, 2(99): 222-224 (pdf).
  5. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 27 [Interactions among food components. Part 27]. Żywność. Nauka. Technologia. Jakość 2015, 3(100): 215-217 (pdf).
  6. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 28 [Interactions among food components. Part 28]. Żywność. Nauka. Technologia. Jakość 2015, 4(101): 201-204 (pdf).
  7. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 29 [Interactions among food components. Part 29]. Żywność. Nauka. Technologia. Jakość 2015, 5(102): 213-216 (pdf).
  8. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 30 [Interactions among food components. Part 30]. Żywność. Nauka. Technologia. Jakość 2015, 6(103): 165-168 (pdf).
  9. Szyc, Anna M.; Fotschki, Joanna; Drabińska, Natalia; Wróblewska, Barbara. Rola cząsteczek mikrorna w patogenezie, diagnostyce i terapii chorób alergicznych. In: Wybrane zagadnienia biologii i medycyny. Red. Skopinska-Różewska, Ewa; Siwicki, Andrzej K.; Zdanowski, Robert. Edycja, Olsztyn 2015 (ISBN 978-83-94917-1-9), 333-344.
  10. Wróblewska, Barbara; Konopka, Iwona. Postęp w badaniach nad zagadnieniem alergii pokarmowej. Bezpieczeństwo i Higiena Żywności 2015, 27-30.

2014

  1. Kalve, Shweta; Fotschki, Joanna; Beeckman, Tom; Vissenberg, Kris; Beemster, Gerrit T. S. Three-dimensional patterns of cell division and expansion throughout the development of Arabidopsis thaliana leaves. Journal of Experimental Botany 2014, 65(22): 6385-6397 (doi: 10.1093/jxb/eru358).
  2. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 19 [Interactions among food components. Part 19]. Żywność. Nauka. Technologia. Jakość 2014, 1(92): 215-217 (pdf).
  3. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 20 [Interactions among food components. Part 20]. Żywność. Nauka. Technologia. Jakość 2014, 2(93): 239-241 (pdf).
  4. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 21 [Interactions among food components. Part 21]. Żywność. Nauka. Technologia. Jakość 2014, 3(94): 206-208 (pdf).
  5. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 22 [Interactions among food components. Part 22]. Żywność. Nauka. Technologia. Jakość 2014, 4(95): 201-203 (pdf).
  6. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 23 [Interactions among food components. Part 23]. Żywność. Nauka. Technologia. Jakość 2014, 5(96): 228-229 (pdf).
  7. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 24 [Interactions among food components. Part 24]. Żywność. Nauka. Technologia. Jakość 2014, 6(97): 197-200 (pdf).
  8. Ogrodowczyk, Anna M.; Fotschki, Joanna; Wróblewska, Barbara. The effect of L. delbruecki ssp. bulgaricus-151 fermented buttermilk beverage on the course of allergic reaction [Wpływ maślanki fermentowanej szczepem L. delbruecki spp. bulgaricus-151 na przebieg reakcji alergicznej]. Episteme. Czasopismo Naukowo-Kulturalne 2014, 22(1): 361-368 (pdf).
  9. Ogrodowczyk, Anna M.; Markiewicz, Lidia H.; Wróblewska, Barbara. Mutations in the filaggrin gene and food allergy. Przegląd Gastroenterologiczny 2014, 9(4): 200-207 (doi: 10.5114/pg.2014.45100).
  10. Szymkiewicz, Agata; Chudzik-Kozłowska, Justyna. Pea proteins immunotherapy in peanut allergic mice model. Acta Alimentaria 2014, 43(2): 193-201 (doi: 10.1556/AAlim.43.2014.2.1).
  11. Teodorowicz, Małgorzata; Świątecka, Dominika; Savelkoul, H.; Wichers, Harru; Kostyra, Elżbieta. Hydrolysates of glycated and heat-treated peanut 7S globulin (Ara h 1) modulate human gut microbial proliferation, survival and adhesion. Journal of Applied Microbiology 2014, 116(2): 424-434 (doi: 10.1111/jam.12358).

2013

  1. Chudzik-Kozłowska, Justyna P.; Złotkowska, Dagmara; Kostyra, Henryk. BALB/C mice as a model for immunogenicity testing of food proteins on the example of egg ovalbumin. Central European Journal of Immunology 2013, 38(4): 430-433 (doi: 10.5114/ceji.2013.39757).
  2. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 13 [Interactions among food components. Part 13]. Żywność. Nauka. Technologia. Jakość 2013, 1(86): 230-232 (pdf).
  3. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 14 [Interactions among food components. Part 14]. Żywność. Nauka. Technologia. Jakość 2013, 2(87): 185-187 (pdf).
  4. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 15 [Interactions among food components. Part 15]. Żywność. Nauka. Technologia. Jakość 2013, 3(88): 200-202 (pdf).
  5. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 16 [Interactions among food components. Part 16]. Żywność. Nauka. Technologia. Jakość 2013, 4(89): 222-224 (pdf).
  6. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 17 [Interactions among food components. Part 17]. Żywność. Nauka. Technologia. Jakość 2013, 5(90): 211-213 (pdf).
  7. Kostyra, Henryk; Kostyra, Elżbieta. Interakcje składników żywności. Część 18 [Interactions among food components. Part 18]. Żywność. Nauka. Technologia. Jakość 2013, 6(91): 219-220 (pdf).
  8. Markiewicz, Lidia H.; Honke, Joanna; Haros, Monika; Świątecka, Dominika; Wróblewska, Barbara. Diet shapes the ability of human intestinal microbiota to degrade phytate – in vitro studies. Journal of Applied Microbiology 2013, 115(1): 247-259 (doi: 10.1111/jam.12204).
  9. Ogrodowczyk, Anna M.; Wróblewska, Barbara; Markiewicz, Lidia H.; Zakrzewska, Magdalena. Possible immunological consequences of filaggrin gene mutation. Case study of 3 year old allergic girl. Central European Journal of Immunology 2013, 38(3): 403-407 (doi: 10.5114/ceji.2013.37747).
  10. Szymkiewicz, Agata; Chudzik-Kozłowska, Justyna. Peanut allergenicity and cross-reactivity with pea proteins in the in vivo model. Polish Journal of Food and Nutrition Sciences 2013, 63(1): 35-42 (doi: 10.2478/v10222-012-0063-7).
  11. Świątecka, Dominika; Markiewicz, Lidia H.; Wróblewska, Barbara. In vitro evaluation of the effect of the buckwheat protein hydrolysate on bacterial adhesion, physiology and cytokine secretion of Caco-2 cells. Central European Journal of Immunology 2013, 38(3): 317-327 (doi: 10.5114/ceji.2013.37753).
  12. Teodorowicz, Małgorzata; Fiedorowicz, Ewa; Kostyra, Henryk; Wichers, Harru; Kostyra, Elżbieta. Effect of Maillard reaction on biochemical properties of peanut 7S gloubulin (Ara h 1) and its interaction with human colon cancer cell line (Caco-2). European Journal of Nutrition 2013, 52(8): 1927-1938 (doi: 10.1007/s00394-013-0494-x).
  13. Wasilewska, Ewa; Złotkowska, Dagmara; Pijagin, Mariola E. Rola mikroflory jelitowej i bakterii probiotycznych w profilaktyce i rozwoju raka jelita grubego [The role of intestinal microflora and probiotic bacteria in prophylactic and development of colorectal cancer]. Postępy Higieny i Medycyny Doświadczalnej 2013, 67: 837-847 (pdf).
  14. Wróblewska, Barbara; Kaliszewska-Suchodoła, Anna; Kołakowski, Piotr; Troszyńska, Agnieszka. The effect of microbial transglutaminase on the immunoreactive and sensory properties of fermented milk beverages. International Journal of Food Science and Technology 2013, 48(5): 1007-1017 (doi: 10.1111/ijfs.12054).

2012

  1. Bielikowicz, Krzysztof; Kostyra, Henryk; Kostyra, Elżbieta; Teodorowicz, Małgorzata; Rigby, Neil; Wojtacha, Paweł. The influence of non-enzymatic glycosylation on physicochemical and biological properties of pea globulin 7S. Food Research International 2012, 48(2): 831-838 (doi: 10.1016/j.foodres.2012.06.028).
  2. Cieślińska, Anna; Kostyra, Elżbieta; Kostyra, Henryk; Oleński, Kamil; Fiedorowicz, Ewa; Kamiński, Stanisław. Milk from cows of different β-casein genotypes as a source of β-casomorphin-7. International Journal of Food Sciences and Nutrition 2012, 63(4): 426-430 (doi: 10.3109/09637486.2011.634785).
  3. Jun, SangMu; Clapp, Beata; Złotkowska, Dagmara; Hoyt, Teri; Holderness, Kathryn; Maddaloni, Massimo; Pascual, David W. Sublingual immunization with adenovirus F protein-based vaccines stimulates protective immunity against botulinum neurotoxin A intoxication. International Immunology 2012, 24(2): 117-128 (doi: 10.1093/intimm/dxr106).
  4. Jun, SangMu; Ochoa-Repáraz, Javier; Złotkowska, Dagmara; Hoyt, Teri; Pascual, David W. Bystander-mediated stimulation of proteolipid protein-specific regulatory T (Treg) cells confers protection against experimental autoimmune encephalomyelitis (EAE) via TGF-ß. Journal of Neuroimmunology 2012, 245(1-2): 39-47 (doi: 10.1016/j.jneuroim.2012.02.003).
  5. Świątecka, Dominika; Markiewicz, Lidia H.; Wróblewska, Barbara. Pea protein hydrolysate as a factor modulating the adhesion of bacteria to enterocytes, epithelial proliferation and cytokine secretion – an in vitro study. Central European Journal of Immunology 2012, 37(3): 227-231 (doi: 10.5114/ceji.2012.30798).
  6. Wróblewska, Barbara; Kaliszewska, Anna. Cow’s milk proteins immunoreactivity and allergenicity in processed food. Czech Journal of Food Sciences 2012, 30(3): 211-219 (pdf).
  7. Zieliński, Henryk; Zielińska, Danuta; Kostyra, Henryk. Antioxidant capacity of a new crispy type food products determined by updated analytical strategies. Food Chemistry 2012, 130(4): 1098-1104 (doi: 10.1016/j.foodchem.2011.08.009).
  8. Złotkowska, Dagmara; Maddaloni, Massimo; Riccardi, Carol; Walters, Nancy; Holderness, Kathryn; Callis, Gayle; Rynda-Apple, Agnieszka; Pascual, David W. Loss of sialic acid binding domain redirects protein σ1 to enhance M cell-directed vaccination. Plos One 2012, 7(4): art. no e36182 (1-12) (doi: 10.1371/journal.pone.0036182).
  9. Złotkowska, Dagmara; Wasilewska, Ewa; Kubicka, Ewa; Wróblewska, Barbara. The effect of pea albumins on immune response in mice. Central European Journal of Immunology 2012, 37(3): 232-236 (doi: 10.5114/ceji.2012.30799).

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Foreign co-operation I&FM

  • Queen’s University Belfast, UK
  • Quadrum (Institute of Food Research), Norwich, UK
  • University Hohenheim, Germany
  • University of Turin, Italy
  • Firmą IN OVO, The Netherlands
  • Firma Microbion, Italy
  • AZTI Technalia, Bilbao, Spain
  • KEKI Central Food Institute, Budapest, Hungary
  • Obihiro University of Agriculture and Veterinary Medicine, Japan
  • University Pierre and Marie Curie in Paris, CNRS Sorbonne University, Paris, France
  • University of Salzburg: Salzburg, Austria
  • INRAE, Clermont-Ferrand, France

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Achievements I&FM

  1. The development of innovative dairy products with unique recipes.
  2. The confirmation of the hypothesis about the immunogenicity of microbial proteins isolated from commensal, probiotic and technologically applied Lactobacillus strains.
  3. The confirmation of the hypothesis about the differentiating potential of the digestion process on the profile and immunogenicity of expressed microbial proteins in the context of their sensitizing potential.
  4. The differentiating effect of lipid composition as an additive to the matrix used for the cultivation of lactic acid bacteria strains on the profile and immunogenicity of microbial proteins in the context of their sensitizing potential has been proven.
  5. The need to introduce a new indicator of food safety, based on microbial proteins immunoreactivity testing, was indicated.
  6. It has been shown that human sera from people sensitized to cows’ milk proteins can react with milk proteins mare at the level of IgE and IgG antibodies, which does not exclude the possibility of cross-reactions.
  7. It has been shown that cross-linking of milk proteins with microbial transglutaminase resulted in a reduction β-lactoglobulin immunoreactivity and increased α-casein immunoreactivity with mice sera.
  8. It has been selected a bacterial strain (L. acidophilus ACD-1), which has a significant ability to reduce the reactivity of mare’s milk proteins with IgE antibodies derived from the serum of patients allergic to cow’s milk proteins
  9. It was found that mare’s milk fermented with bacterial strain L. plantarum 110 caused the low IgG reaction with sera from patients with cow’s milk protein allergy.
  10. Phytic acid in the presence of butyric acid (a metabolite of intestinal bacteria) stimulates the processes of cell death of cancer colonocytes, while in healthy colonocytes it initiates regeneration pathways.
  11. Phytic acid hydrolysate reduces the excessive pro-inflammatory reaction of cancer colonocytes to intestinal bacteria while remaining neutral for the immune response of healthy colonocytes.
  12. Increased immunoreactivity of thermalized milk proteins beta-lactoglobulin and alpha-lactalbumin has been demonstrated.
  13. Glycation of ovalbumin and beta-lactalbumin modulates the T-lymphocyte profile.
  14. Selected probiotic preparations reduce the humoral response to cow’s milk beta-lactoglobulin and modulate the profile of immunocompetent cells.
  15. The therapeutic effect of S. thermophilus strain MK-10 and L. bulgaricus 151 on intestinal inflammation induced in a mouse model was demonstrated by affecting the intestinal microbiota and modulating the T-cell profile.

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