Meeting with Prof. Carsten Carlberg – report from ERA Chair WELCOME2 press conference

WELCOME2

The Institute’s new research project will be headed by Prof. Carsten Carlberg, a prominent biochemist, and vitamin D specialist. It will aim to create a Centre of Excellence dedicated to nutrigenomics and help in the fight against diet-related diseases. Prof. Carlberg was officially introduced to the media and people from the local scientific and business community on March 23 at the Olsztyn Science and Technology Park campus.

Prof. Carsten Carlberg was selected as ERA Chair holder under the WELCOME grant, winning an international competition in which candidates were evaluated by renowned scientists from Poland, France, Germany, and Greece.

„Our quality of life is determined by two components: 20% by genes that we have received from our parents and with which we can do little, and up to 80% by epigenetic factors that we can influence. The quality of our lives depends on us alone” – says Professor Carlberg in the opening lecture.

Professor Carlberg gave his lecture before distinguished guests gathered in the Olsztyn Science and Technology Park, which included representatives of the world of science, business, local doctors, management staff of the institutions supporting the development of innovation in the region, representatives of student organizations, associations working to improve the quality of human life, social activists, employees of the Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences, as well as the media. The welcome conference was honored by the presence of Gustaw Marek Brzezin, Marshal of the Warmińsko-Mazurskie Voivodship. Other guests included: Kazimierz Kujawa, Chairman of the Board of MASPEX Group; Prof. Andrzej Babuchowski, President of the Institute of Innovation of the Dairy Industry SM Mlekpol; Prof. Sergiusz Nawrocki, medical oncologist, Vice-Rector for Collegium Medicum UWM; Prof. Małgorzata Darewicz, Dean of the Faculty of Food Sciences UWM; Maria Borzym, Director of Olsztyn Science and Technology Park; Anna Sliwinska, President of the Polish Association of Diabetes Mellitus and others.

New perspectives

The conference was opened by Prof. Mariusz Piskuła, who presented the importance of the WELCOME2 project for the whole region. He also stressed that the choice of Prof. Carsten Carlberg for the position of ERA Chair was not accidental – there was a tough competition. Out of 13 candidates, it was Prof. Carlberg who presented the vision that best fit the impacts we want to achieve.

„The dimension of this project is at least regional. We do not want to build a strong position of the Institute, but to share our achievements with everyone in the immediate vicinity. We want to emanate and transfer our experiences for the development of the region, science in Olsztyn, breaking with the stereotype of Olsztyn as a city in the east, outside the center of important scientific events that take place in Poland” – said Prof. Mariusz Piskuła.

After the speech of Prof. Piskuła, the floor was taken by Gustaw Marek Brzezin, Marshal of the Warmińsko-Mazurskie Voivodship, who noted that ERA Chair WELCOME2 is an extremely important project for him, not only for the sake of the function he holds, but also for personal reasons.

„It is a great honor for me, because I treat it personally, but also as a representative of the local government, to be on this beautiful journey to a better future of the region of Warmia and Mazury. The honor is even greater because we see how much potential we can derive from the world of science, local government, and practice to change the region and stereotypes. The Warmia and Mazury region can implement EU policy as the 21st-century demands” – said Gustaw Marek Brzezin.

When Prof. Carlberg began his lecture, he immediately outlined his goals in creating the Center of Excellence in nutrigenomics at the Institute. Prof. Carlberg will continue his ongoing work of more than 30 years related to vitamin D. Some time ago, he discovered that people can be classified into three groups: high, mid and low responders to vitamin D exposure. That’s why each of us needs a slightly different, strictly personalized dose – there’s no such thing as a „gold standard” in this case.

„Each of us has different needs, different predispositions. Vitamin D supplementation for everyone should look a little different. With specialized testing, we can find out what dose is right for us. If we don’t want to do this, I recommend taking a low dose of vitamin D, which according to my research is five times more than the pharmacists suggest anyway. We will not harm ourselves with this, and we will meet our body’s need for this compound” – said Prof. Carlberg.

The audience enthusiastically reacted to ERA Chair WELCOME2’s presentation, provoking interesting questions. Prof. Babuchowski asked whether vitamin D can be overdosed? In turn, Prof. Sergiusz Nawrocki raised the issue of vitamin D supplementation in Finland, where Prof. Carlberg had previously worked. Guests were also interested in why some people respond well to vitamin D supplementation, while others do not. Prof. Carlberg tried to dispel all doubts of the attendees comprehensively.

Everyone will have their own „digital twin”

One of the most important goals of the Centre’s work will be to develop the so-called „digital twins”, i.e. virtual models of real people, on whom interventions related to the selection of diet, physical activity, and medication will be „tested”. This will be one of the elements of personalized medicine, which is considered to be the future of medical care. Due to the need for numerous computer simulations, Prof. Carlberg is looking for biologists and physicians, and computer scientists to join his team.

„A hundred years ago, people were making prototypes of airplanes, but they were operating somewhat blindly. Some of them flew, some of them went down right after takeoff. By trial and error, they finally figured out what an airplane should look like, and that’s how it is today. Today such actions are unthinkable. Now engineers digitally create every part of an airplane before they manufacture it. The digital twin is intended to serve the same function – a virtual model for testing diets and drugs” – explained Prof. Carlberg.

Prof. Carlberg’s welcome conference is only the first chord of his work in Olsztyn. The best – from a scientific point of view – is yet to come.

ERA Chair WELCOME2

The European ERA Chairs H2020 grant worth EUR 2.5 million, entitled „Establishment of a Centre of Excellence in Olsztyn. „Establishment of a Centre of Excellence in the area of nutrigenomics for improved health and quality of life” (WELCOME2) was awarded to the Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences in 2020. The Institute is one of seven ERA Chairs laureates in Poland in the program’s history to date. Its realization will allow the creation in the Institute an international research team led by world-class scientists and to carry out structural changes leading to ensure that the Institute’s research conditions meet the standards of the European Research Area.

More about the ERA Chair WELCOME2 project at: https://welcome2.pan.olsztyn.pl/

Gazeta Wyborcza

Olsztyn24

olsztyn.com.pl

TVP3 Olsztyn

Melo Radio

Marshall of Warmia and Mazury Gustaw Marek Brzezin

Prof. Monika Kaczmarek


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IARFR PAS joins NuGO

At the initiative of WELCOME2 ERA Chair holder, prof. Carsten Carlberg, the Institute of Animal Reproduction and Food Research has joined the European Organization of Nutrigenomics NuGO. NuGO is a prestiogious international association of universities and research institutes focusing on the joint development of the research areas of molecular nutrition, personalised nutrition, nutrigenomics and nutritional systems biology.

NuGO has a mission focused on:

  • stimulating developments in molecular nutrition, personalised nutrition, nutrigenomics, nutrigenetics and nutritional systems biology, and incorporating these aspects in nutrition and health research, by joint research projects, conferences, workshops and training. NuGO can join as partner in your research project.
  • shaping the nutrition bioinformatics infrastructure, by initiating, coordinating and facilitating projects in this area, and by hosting the dissemination of all data, results and information.

Among NuGO member organisations we may find such as Wageningen University & Research, Quadram Institute Bioscience, Ghent University or University of Melbourne. See the full list here.

SEMINARS

NuGO has just announced a series of webinars 2022 ECN NuGO, and the first of them „Precision Nutrition – Fact or Fiction; Using multi-omics to unravel the multiple inter-related determinants of our individual responses to food” will be held 30th March at 11:00AM (CEST). The speakers will be Drs. Sarah Berry and Kate Bermingham from King’s College London.

Click here to register for the event.

Summary

There is growing awareness of the need to move beyond the ‘one-size-fits-all’ approach in nutritional advice. However, for personalised nutrition to become a reality, large-scale, high precision data integrating multiple dietary, lifestyle, physiological, genetic and metagenomic data is required. This webinar will explore 1) why we need personalised approaches to nutrition advice, 2) the current status of personalised nutrition and remote clinical trials and 3) new developments with a focus on the ZOE PREDICT programme of research. The ZOE PREDICT programme is the largest ongoing programme of personalised nutrition (n>20,000) assessing the genetic, metagenomic, metabolomic and meal-context drivers of metabolic responses to predict individual responses to food using AI. This research is at the forefront of developments in personalised nutrition and is forging a new way forward in the design and implementation of large-scale remote nutrition research studies integrating novel technologies, citizen science and AI. The PREDICT programme has demonstrated the large and potentially modifiable variation in metabolic responses to identical meals in healthy people and the role that ‘what’ we eat, ‘who’ we are and ‘how’ we eat plays in shaping our responses.

Speakers:

Sarah Berry is a Reader in Nutritional Sciences at King’s College London. Her research interests relate to the influence of dietary components on cardiometabolic disease risk, with particular focus on; personalised nutrition, postprandial lipid metabolism and food and fat structure. Since commencing her research career at King’s, she has been the academic leader for more than 30 human nutrition studies in cardio-metabolic health. Sarah is also the lead nutritional scientist on the PREDICT programme of research, assessing the genetic, metabolic, metagenomic, and meal-dependent effects on metabolic responses to food in >20,000 individuals in the UK and US. This research is at the forefront of developments in personalised nutrition and is forging a new way forward in the design and implementation of large-scale remote nutrition research studies integrating novel technologies, citizen science and AI.

Kate Bermingham is a Post-Doctoral Researcher in the Department of Twin Research and Genetic Epidemiology at King’s College London. Her research areas of interest relate to understanding inter and intra-variation in dietary, anthropometric and metabolic phenotypes, and determining how individuals respond to different diets and lifestyles with a view to informing personalised nutrition strategies.

 

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Wiki Science Competition 2021

The photo of prof. Agnieszka Wacławik taken by Radosław Dąbrowski during her research work won the Wiki Science Competition 2021 under the „Women in Science” category. It will enrich the catalog of free multimedia that will help illustrate Wikipedia and promote science.

In this year’s edition of the Wiki Science Competition 2021 in the category „Women in science, especially women in STEM, portraits of female scientists” the Polish jury awarded a distinction and submitted to the international stage the photo of prof. Agnieszka Wacławik, investigating molecular processes of pregnancy development in mammals. The author of the photo is Radosław Dąbrowski, a photographer living in Targów. He contacted Dr. Wacławik after reading information about her distinction on the TOP 2% list of the most influential scientists in the world.

The Wiki Science Competition is one of the world’s largest international photo contests documenting the world of science. It takes place every 2 years in two stages: national and international. It is aimed at all scientists, scientific institutions and science lovers, and photographers who are close to the idea of promoting and disseminating science in the modern world.

The Wiki Science Competition aims to encourage the creation and sharing of creative works depicting the world of science. The submitted files, which show, for example, research facilities, scientists at work, or research equipment, will help to illustrate the thousands of articles in the various language versions of Wikipedia, thus contributing to the promotion of science, the work of scientists, and the results of scientific research.

Click here for the full list of featured images in the Wiki Science Competition 2021.

 

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WELCOME2 ERA Chair holder nominated

Prof. Carsten Carlberg, a world-class biochemist in the area of research on vitamin D, has been nominated for the position of ERA Chair holder in the Institute of Animal Reproduction and Food Research PAS. As a part of WELCOME2 H2020 grant he will lead the creation of an interdisciplinary Centre of Excellence exploiting the tools of nutrigenomics to assess the impact of nutrition on the (epi)genetic predisposition to diet-related diseases. Prof. Carlberg was selected in an international open call, assessed by a body of scientists from Poland, France, Germany and Greece. (więcej…)

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2022 Call for PhD students in Nutrigenomics at IAR&FR PAS, Poland

The Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn, Poland is looking for three PhD students. The PhD students will be part of an interdisciplinary team of researchers led by Prof. Carsten Carlberg with the goal to investigate the effect of vitamin D and other nutritional compounds on changes of the epigenome and transcriptome of tissues and cell types of healthy and (pre)diseased individuals. (więcej…)

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2022 Call for a position of a Postdoc in Nutrigenomics at IAR&FR PAS, Poland

The Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn, Poland is looking for two full-time Postdoctoral Associates. The Postdoctoral Associates will be part of an interdisciplinary team of researchers led by Prof. Carsten Carlberg with the goal to investigate the effect of vitamin D and other nutritional compounds on changes of the epigenome and transcriptome of tissues and cell types of healthy and (pre)diseased individuals. (więcej…)

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